With the context of the global climate warming,the potential evapotranspiration (ET_0) in the sandy land of Wushen County in the Mu Us Desert in recent 46 years was in a significant downward trend.The amount of precipitation rose slightly,the trend of warm-humid in the area was obvious.The ET_0 in Naiman County of the Khorchin sandy land increased gradually,the rainfall decreased slightly.There was a weak tendency of warming and drying.The ET_0 in Wushen County was positively correlated with the wind speed,the temperature was negatively correlated with the ET_0,and the ET_0 only had a significant negative correlation with the lowest temperature.The ET_0 in Naiman County was consistent with the trend of temperature,the ET_0 was positively correlated with maximum temperature,and the ET_0 was significantly negatively correlated with relative humidity.The contribution rate of wind speed was 58.53% to the ET_0 in Wushen County,and the overall contribution rate of temperature was 39.98%.The contribution rate of wind speed was 38.81% to the ET_0 in Naiman County,and the overall contribution rate of temperature was 56.99%.The main meteorological factors affecting two sandy areas in east and west Inner Mongolia were significantly different,the sandy land in the western area was mainly affected by wind speed,and the eastern area was mainly affected by temperature.