The changes in temperatures and precipitation in Northwest China have aroused widespread concern in society. The Ulungur River basin located in the southeastern of Altay region, and originated in the southeast slope of Altay Mountains, the seasonal snow cover and summer rainfall is the main supply water source. Based on the analysis of the hydrological and meteorological data in the past 50 years, the results showed that the temperatures and precipitation is increasing fluctuated, and the extent of rise is higher than that of North Xinjiang. The runoff is increasing in April to May, and decreasing in June to August, which indicating that there is an early trend in snow melting. The runoff affected significantly by temperature indicating that the runoff is more sensitive to temperature. The temperatures rise and the precipitation increases in winter resulted in the snowmelt floods and the peak flow increasing, and the destructive increased.