Select the Mahai Saline Lake in Qaidam Basin as an object of study. A total of 75 specific yield samples were collected from 11 sampling points in the research area, and the depth range is 1.61-148.5 m. The previous testing data of 72 specific yield samples were collected from 37 sampling points in the research area were obtained. We totally got 145 specific yield samples from 48 sampling points. According to the measured specific yield data, adopting mathematical statistics methods to analyze the qaidam basin mohair salt lake brine formations, distribution of water level changes. The specific yield in brine aquifer characteristics of distribution and variation of the saline lake in Qaidam Basin is studied by statistical analysis. It is found that: 1) There are larger difference of specific yield in the horizontal direction. The data of W_Ⅰ to W_Ⅴ brine aquifer are between 0-0.263 5, 0.009 4-0.209 9, 0.006 2-0.135 9, 0.006 2-0.135 9, 0-0.107 7. The specific yield of different brine aquifers have smaller values in the sample point MHK-022 to MHK-026, and the average is less than 0.06. While in the northeast of the salt lake, the specific yield of different brine aquifers have bigger values and the average is greater than 0.08.2) Specific yield in the vertical direction affected by the hydrostatic pressure of strata.With the increase of the depth the specific yield were decreases. 3) Specific yield in the vertical direction also shows cyclicity change characteristics. The emergence of the depositional cycle may be right to reflect climate fluctuations during the period of the salt deposits.