DOI: 10.1016/j.scitotenv.2019.135263
论文题名: A global environmental health perspective and optimisation of stress
作者: Agathokleous E. ; Calabrese E.J.
刊名: Science of the Total Environment
ISSN: 489697
出版年: 2020
卷: 704 语种: 英语
英文关键词: Contamination
; Dose–response relationship
; Environmental pollution
; Global environmental change
; Hormesis
; Stress biology
Scopus关键词: Contamination
; Environmental engineering
; Pollution
; Adaptive mechanism
; Biological performance
; Environmental change
; Environmental health
; Environmental pollutions
; Global environmental change
; Hormesis
; Stress response
; Pollution control
; dose-response relationship
; environmental fate
; environmental stress
; environmental values
; literature review
; optimization
; biodiversity
; contamination
; drug megadose
; environmental change
; environmental health
; hormesis
; low drug dose
; physiological stress
; review
; adaptation
; hormesis
; human
; Adaptation, Physiological
; Environmental Health
; Hormesis
; Humans
; Stress, Physiological
英文摘要: The phrase “what doesn't kill us makes us stronger” suggests the possibility that living systems have evolved a spectrum of adaptive mechanisms resulting in a biological stress response strategy that enhances resilience in a targeted quantifiable manner for amplitude and duration. If so, what are its evolutionary foundations and impact on biological diversity? Substantial research demonstrates that numerous agents enhance biological performance and resilience at low doses in a manner described by the hormetic dose response, being inhibitory and/or harmful at higher doses. This Review assesses how environmental changes impact the spectrum and intensity of biological stresses, how they affect health, and how such knowledge may improve strategies in confronting global environmental change. © 2019 Elsevier B.V. Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/159217
Appears in Collections: 气候变化与战略
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作者单位: Institute of Ecology, School of Applied Meteorology, Nanjing University of Information Science and Technology (NUIST), Ningliu Rd. 219, Nanjing, Jiangsu 210044, China; Professor of Toxicology, Department of Environmental Health Sciences, Morrill I, N344; University of Massachusetts, Amherst, MA 01003, United States
Recommended Citation:
Agathokleous E.,Calabrese E.J.. A global environmental health perspective and optimisation of stress[J]. Science of the Total Environment,2020-01-01,704