DOI: 10.1104/pp.19.01154
论文题名: Dark-Induced Senescence Causes Localized Changes in DNA Methylation
作者: Trejo-Arellano M.S. ; Mehdi S. ; de Jonge J. ; Dvorák Tomastíková E. ; Köhler C. ; Hennig L.
刊名: Plant physiology
ISSN: 15322548
出版年: 2020
卷: 182, 期: 2 语种: 英语
英文摘要: Senescence occurs in a programmed manner to dismantle the vegetative tissues and redirect nutrients towards metabolic pathways supporting reproductive success. External factors can trigger the senescence program as an adaptive strategy, indicating that this terminal program is controlled at different levels. It has been proposed that epigenetic factors accompany the reprogramming of the senescent genome; however, the mechanism and extent of this reprogramming remain unknown. Using bisulphite conversion followed by sequencing, we assessed changes in the methylome of senescent Arabidopsis (Arabidopsis thaliana) leaves induced by darkness and monitored their effect on gene and transposable element (TE) expression with transcriptome sequencing. Upon dark-induced senescence, genes controlling chromatin silencing were collectively down-regulated. As a consequence, the silencing of TEs was impaired, causing in particular young TEs to become preferentially reactivated. In parallel, heterochromatin at chromocenters was decondensed. Despite the disruption of the chromatin maintenance network, the global DNA methylation landscape remained highly stable, with localized changes mainly restricted to CHH methylation. Together, our data show that the terminal stage of plant life is accompanied by global changes in chromatin structure but only localized changes in DNA methylation, adding another example of the dynamics of DNA methylation during plant development. © 2020 American Society of Plant Biologists. All Rights Reserved. Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/159518
Appears in Collections: 气候变化与战略
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作者单位: Swedish University of Agricultural Sciences, Department of Plant Biology and Linnean Center for Plant BiologyUppsala SE-75007, Sweden; Swedish University of Agricultural Sciences, Department of Plant Biology and Linnean Center for Plant BiologyUppsala SE-75007, Sweden
Recommended Citation:
Trejo-Arellano M.S.,Mehdi S.,de Jonge J.,et al. Dark-Induced Senescence Causes Localized Changes in DNA Methylation[J]. Plant physiology,2020-01-01,182(2)