DOI: 10.1098/rsbl.2019.0889
论文题名: Chronic water restriction triggers sex-specific oxidative stress and telomere shortening in lizards
作者: Dupoué A. ; Angelier F. ; Ribout C. ; Meylan S. ; Rozen-Rechels D. ; Decencière B. ; Agostini S. ; Le Galliard J.-F.
刊名: Biology Letters
ISSN: 17449561
出版年: 2020
卷: 16, 期: 2 语种: 英语
英文关键词: Aging
; Antioxidant
; Longevity
; Oxidative damage
; Sex
; Water
Scopus关键词: Animalia
; Squamata
; Zootoca vivipara
英文摘要: Animals use a variety of strategies to avoid acute dehydration and death. Yet, how chronic exposure to sub-lethal dehydration may entail physiological and fitness costs remains elusive. In this study, we experimentally tested if water restriction causes increased oxidative stress (OS) and telomere length (TL) shortening, two well-described mediators of environment–fitness relationships. We exposed 100 yearling female and male common lizards (Zootoca vivipara) either to a 51-day period of water restriction or to water ad libitum, followed by 45 days in common garden outdoor conditions. We measured the kinetic changes in OS and TL and found that water-restricted males had enhanced antioxidant defences and decreased oxidative damage at day 36, whereas females did not immediately respond. A month and a half after water restriction, both sexes experienced a drop in antioxidant capacity but only males exhibited significant TL shortening. In the following 3 years, we found that lizards with longer initial TL and those who maintained stronger antioxidant defences experienced higher longevity, irrespective of sex and water restriction. Together, these results unravelled sex-specific responses to water restriction, with potential applications in better understanding the physiological costs of increasing summer droughts as a result of global climate change. © 2020 The Author(s) Published by the Royal Society. All rights reserved. Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/159813
Appears in Collections: 气候变化与战略
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作者单位: iEES Paris, Sorbonne Université, CNRS, UMR 7618, 4 place Jussieu, Paris, 75005, France; CEBC, La Rochelle Université, CNRS UMR 7372, Beauvoir sur Niort, 79360, France; École Normale Supérieure, PSL Research University, Département de Biologie, CNRS, UMS 3194, Centre de Recherche en écologie Expérimentale et Prédictive (CEREEP-Ecotron IleDeFrance), 78 rue du Château, Saint-Pierre-lès-Nemours, 77140, France
Recommended Citation:
Dupoué A.,Angelier F.,Ribout C.,et al. Chronic water restriction triggers sex-specific oxidative stress and telomere shortening in lizards[J]. Biology Letters,2020-01-01,16(2)