globalchange  > 气候变化与战略
DOI: 10.1073/pnas.1916935117
论文题名:
Bacterial flagellar motor PL-ring disassembly subcomplexes are widespread and ancient
作者: Kaplan M.; Sweredoski M.J.; Rodrigues J.P.G.L.M.; Tocheva E.I.; Chang Y.-W.; Ortega D.R.; Beeby M.; Jensen G.J.
刊名: Proceedings of the National Academy of Sciences of the United States of America
ISSN: 0027-8424
出版年: 2020
卷: 117, 期:16
起始页码: 8941
结束页码: 8947
语种: 英语
英文关键词: Cryo-electron tomography ; Evolution ; Flagellar motor
Scopus关键词: article ; electron tomography ; flagellum ; outer membrane ; bacterial gene ; bacterial outer membrane ; bacterium ; biology ; cryoelectron microscopy ; cytology ; electron tomography ; genetics ; metabolism ; phylogeny ; species differentiation ; ultrastructure ; bacterial protein ; flgI protein, Bacteria ; outer membrane protein ; Bacteria ; Bacterial Outer Membrane ; Bacterial Outer Membrane Proteins ; Bacterial Proteins ; Computational Biology ; Cryoelectron Microscopy ; Electron Microscope Tomography ; Flagella ; Genes, Bacterial ; Genetic Speciation ; Phylogeny
英文摘要: The bacterial flagellum is an amazing nanomachine. Understanding how such complex structures arose is crucial to our understanding of cellular evolution. We and others recently reported that in several Gammaproteobacterial species, a relic subcomplex comprising the decorated P and L rings persists in the outer membrane after flagellum disassembly. Imaging nine additional species with cryoelectron tomography, here, we show that this subcomplex persists after flagellum disassembly in other phyla as well. Bioinformatic analyses fail to show evidence of any recent horizontal transfers of the P- and L-ring genes, suggesting that this subcomplex and its persistence is an ancient and conserved feature of the flagellar motor. We hypothesize that one function of the P and L rings is to seal the outer membrane after motor disassembly. © 2020 National Academy of Sciences. All rights reserved.
Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/163474
Appears in Collections:气候变化与战略

Files in This Item:

There are no files associated with this item.


作者单位: Kaplan, M., Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, United States; Sweredoski, M.J., Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, United States; Rodrigues, J.P.G.L.M., Department of Structural Biology, Stanford University, Stanford, CA 94305, United States; Tocheva, E.I., Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, United States, Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver, BC V6T 1Z3, Canada; Chang, Y.-W., Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, United States, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States; Ortega, D.R., Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, United States; Beeby, M., Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, United States, Department of Life Sciences, Imperial College London, South Kensington Campus, London, SW7 2AZ, United Kingdom; Jensen, G.J., Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, United States, Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA 91125, United States

Recommended Citation:
Kaplan M.,Sweredoski M.J.,Rodrigues J.P.G.L.M.,et al. Bacterial flagellar motor PL-ring disassembly subcomplexes are widespread and ancient[J]. Proceedings of the National Academy of Sciences of the United States of America,2020-01-01,117(16)
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Kaplan M.]'s Articles
[Sweredoski M.J.]'s Articles
[Rodrigues J.P.G.L.M.]'s Articles
百度学术
Similar articles in Baidu Scholar
[Kaplan M.]'s Articles
[Sweredoski M.J.]'s Articles
[Rodrigues J.P.G.L.M.]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Kaplan M.]‘s Articles
[Sweredoski M.J.]‘s Articles
[Rodrigues J.P.G.L.M.]‘s Articles
Related Copyright Policies
Null
收藏/分享
所有评论 (0)
暂无评论
 

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.