globalchange  > 气候变化与战略
DOI: 10.1073/pnas.1922851117
论文题名:
Distance metrics for ranked evolutionary trees
作者: Kim J.; Rosenberg N.A.; Palacios J.A.
刊名: Proceedings of the National Academy of Sciences of the United States of America
ISSN: 0027-8424
出版年: 2020
卷: 117, 期:46
起始页码: 28876
结束页码: 28886
语种: 英语
英文关键词: Coalescent | distance metric | phylogenetics | ranked genealogy | ranked tree shape
Scopus关键词: Article ; data analysis ; evolution ; genealogy ; Influenza A virus (H3N2) ; intermethod comparison ; phylogenetic tree ; phylogenetic tree construction method ; population size ; priority journal ; simulation ; statistical distribution ; uncertainty
英文摘要: Genealogical tree modeling is essential for estimating evolutionary parameters in population genetics and phylogenetics. Recent mathematical results concerning ranked genealogies without leaf labels unlock opportunities in the analysis of evolutionary trees. In particular, comparisons between ranked genealogies facilitate the study of evolutionary processes of different organisms sampled at multiple time periods. We propose metrics on ranked tree shapes and ranked genealogies for lineages isochronously and heterochronously sampled. Our proposed tree metrics make it possible to conduct statistical analyses of ranked tree shapes and timed ranked tree shapes or ranked genealogies. Such analyses allow us to assess differences in tree distributions, quantify estimation uncertainty, and summarize tree distributions. We show the utility of our metrics via simulations and an application in infectious diseases. © 2020 National Academy of Sciences. All rights reserved.
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资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/163947
Appears in Collections:气候变化与战略

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作者单位: Kim, J., Department of Biology, Stanford University, Stanford, CA 94305, United States; Rosenberg, N.A., Department of Biology, Stanford University, Stanford, CA 94305, United States; Palacios, J.A., Department of Statistics, Stanford University, Stanford, CA 94305, United States, Department of Biomedical Data Science, Stanford School of Medicine, Stanford, CA 94305, United States

Recommended Citation:
Kim J.,Rosenberg N.A.,Palacios J.A.. Distance metrics for ranked evolutionary trees[J]. Proceedings of the National Academy of Sciences of the United States of America,2020-01-01,117(46)
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