DOI: 10.1111/ele.13831
论文题名: Interplay of population size and environmental fluctuations: A new explanation for fitness cost rarity in asexuals
作者: Chavhan Y. ; Malusare S. ; Dey S.
刊名: Ecology Letters
ISSN: 1461023X
出版年: 2021
卷: 24, 期: 9 起始页码: 1943
结束页码: 1954
语种: 英语
中文关键词: costs of adaptation
; ecological specialisation
; experimental evolution
; fluctuating environments
; maladaptation
; mutation fixation
; mutation supply
; whole-genome whole-population sequencing
英文关键词: Escherichia coli
英文摘要: Theoretical models of ecological specialisation commonly assume that adaptation to one environment leads to fitness reductions (costs) in others. However, experiments often fail to detect such costs. We addressed this conundrum using experimental evolution with Escherichia coli in several constant and fluctuating environments at multiple population sizes. We found that in fluctuating environments, smaller populations paid significant costs, but larger ones avoided them altogether. Contrastingly, in constant environments, larger populations paid more costs than the smaller ones. Overall, large population sizes and fluctuating environments led to cost avoidance only when present together. Mutational frequency distributions obtained from whole-genome whole-population sequencing revealed that the primary mechanism of cost avoidance was the enrichment of multiple beneficial mutations within the same lineage. Since the conditions revealed by our study for avoiding costs are widespread, it provides a novel explanation of the conundrum of why the costs expected in theory are rarely detected in experiments. © 2021 John Wiley & Sons Ltd. Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/166793
Appears in Collections: 气候变化与战略
There are no files associated with this item.
作者单位: Indian Institute of Science Education and Research (IISER) Pune, Pune, Maharashtra, India; Gaia Doctoral School, Institut des sciences de l'évolution (ISEM), 1093-1317 Route de Mende, Montpellier, 34090, France
Recommended Citation:
Chavhan Y.,Malusare S.,Dey S.. Interplay of population size and environmental fluctuations: A new explanation for fitness cost rarity in asexuals[J]. Ecology Letters,2021-01-01,24(9)