全球变化知识资源中心

Knowledge Resources Center for Global Change


Email:
Passwd
验证:
	换一张
Have you forgotten your password? Stay signed in Log In

globalchange > 过去全球变化的重建

DOI:	10.1371/journal.pone.0085631
论文题名:	Mutation and Selection Cause Codon Usage and Bias in Mitochondrial Genomes of Ribbon Worms (Nemertea)
作者:	Haixia Chen; Shichun Sun; Jon L. Norenburg; Per Sundberg
刊名:	PLOS ONE
ISSN:	1932-6203
出版年:	2014
发表日期:	2014-1-15
卷:	9, 期:1
语种:	英语
英文关键词:	Nemertea ; Mitochondria ; Invertebrate genomics ; Transfer RNA ; Anticodons ; Paleogenetics ; Genome complexity ; Mitochondrial DNA
英文摘要:	The phenomenon of codon usage bias is known to exist in many genomes and it is mainly determined by mutation and selection. To understand the patterns of codon usage in nemertean mitochondrial genomes, we use bioinformatic approaches to analyze the protein-coding sequences of eight nemertean species. Neutrality analysis did not find a significant correlation between GC12 and GC3. ENc-plot showed a few genes on or close to the expected curve, but the majority of points with low-ENc values are below it. ENc-plot suggested that mutational bias plays a major role in shaping codon usage. The Parity Rule 2 plot (PR2) analysis showed that GC and AT were not used proportionally and we propose that codons containing A or U at third position are used preferentially in nemertean species, regardless of whether corresponding tRNAs are encoded in the mitochondrial DNA. Context-dependent analysis indicated that the nucleotide at the second codon position slightly affects synonymous codon choices. These results suggested that mutational and selection forces are probably acting to codon usage bias in nemertean mitochondrial genomes.
URL:	http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0085631&type=printable
Citation statistics:
资源类型:	期刊论文
标识符:	http://119.78.100.158/handle/2HF3EXSE/18965
Appears in Collections:	过去全球变化的重建影响、适应和脆弱性科学计划与规划气候变化与战略全球变化的国际研究计划气候减缓与适应气候变化事实与影响

Files in This Item:	Download All

File Name/ File Size	Content Type	Version	Access	License
journal.pone.0085631.PDF（445KB）	期刊论文	作者接受稿	开放获取	CC BY-NC-SA	View Download

作者单位:

Department of Biological and Environmental Sciences, University of Gothenburg, Sweden;Institute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao, China;Department of Invertebrate Zoology, Smithsonian's National Museum of Natural History, Washington D.C., United States of America;Department of Biological and Environmental Sciences, University of Gothenburg, Sweden

Recommended Citation:

Haixia Chen,Shichun Sun,Jon L. Norenburg,et al. Mutation and Selection Cause Codon Usage and Bias in Mitochondrial Genomes of Ribbon Worms (Nemertea)[J]. PLOS ONE,2014-01-01,9(1)

Service
	Recommend this item
	Sava as my favorate item
	Show this item's statistics
	Export Endnote File
Google Scholar
	Similar articles in Google Scholar
	[Haixia Chen]'s Articles
	[Shichun Sun]'s Articles
	[Jon L. Norenburg]'s Articles
百度学术
	Similar articles in Baidu Scholar
	[Haixia Chen]'s Articles
	[Shichun Sun]'s Articles
	[Jon L. Norenburg]'s Articles
CSDL cross search
	Similar articles in CSDL Cross Search
	[Haixia Chen]‘s Articles
	[Shichun Sun]‘s Articles
	[Jon L. Norenburg]‘s Articles
Related Copyright Policies
Null
收藏/分享