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globalchange > 过去全球变化的重建

DOI:	10.1371/journal.pone.0084578
论文题名:	Diatoms: A Novel Source for the Neurotoxin BMAA in Aquatic Environments
作者:	Liying Jiang; Johan Eriksson; Sandra Lage; Sara Jonasson; Shiva Shams; Martin Mehine; Leopold L. Ilag; Ulla Rasmussen
刊名:	PLOS ONE
ISSN:	1932-6203
出版年:	2014
发表日期:	2014-1-2
卷:	9, 期:1
语种:	英语
英文关键词:	Diatoms ; Cyanobacteria ; Amyotrophic lateral sclerosis ; Marine biology ; Germanium ; Phytoplankton ; Swedes ; Aquatic environments
英文摘要:	Amyotrophic lateral sclerosis (ALS) or Lou Gehrig’s disease is a neurological disorder linked to environmental exposure to a non-protein amino acid, β-N-methylamino-L-alanine (BMAA). The only organisms reported to be BMAA-producing, are cyanobacteria – prokaryotic organisms. In this study, we demonstrate that diatoms – eukaryotic organisms – also produce BMAA. Ultra-high-performance liquid chromatography coupled with tandem mass spectrometry revealed the occurrence of BMAA in six investigated axenic diatom cultures. BMAA was also detected in planktonic field samples collected on the Swedish west coast that display an overrepresentation of diatoms relative to cyanobacteria. Given the ubiquity of diatoms in aquatic environments and their central role as primary producers and the main food items of zooplankton, the use of filter and suspension feeders as livestock fodder dramatically increases the risk of human exposure to BMAA-contaminated food.
URL:	http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0084578&type=printable
Citation statistics:
资源类型:	期刊论文
标识符:	http://119.78.100.158/handle/2HF3EXSE/19723
Appears in Collections:	过去全球变化的重建影响、适应和脆弱性科学计划与规划气候变化与战略全球变化的国际研究计划气候减缓与适应气候变化事实与影响

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File Name/ File Size	Content Type	Version	Access	License
journal.pone.0084578.PDF（878KB）	期刊论文	作者接受稿	开放获取	CC BY-NC-SA	View Download

作者单位:

Department of Analytical Chemistry, Stockholm University, Stockholm, Sweden;Department of Ecology, Environment and Plant Sciences, Stockholm University, Stockholm, Sweden;Department of Ecology, Environment and Plant Sciences, Stockholm University, Stockholm, Sweden;Department of Ecology, Environment and Plant Sciences, Stockholm University, Stockholm, Sweden;Sustainable Agro-ecosystems and Bioresources Department, IASMA Research and Innovation Centre - Fondazione Edmund Mach, Trento, Italy;Department of Analytical Chemistry, Stockholm University, Stockholm, Sweden;Department of Analytical Chemistry, Stockholm University, Stockholm, Sweden;Department of Ecology, Environment and Plant Sciences, Stockholm University, Stockholm, Sweden

Recommended Citation:

Liying Jiang,Johan Eriksson,Sandra Lage,et al. Diatoms: A Novel Source for the Neurotoxin BMAA in Aquatic Environments[J]. PLOS ONE,2014-01-01,9(1)

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