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DOI:	10.1371/journal.pone.0092101
论文题名:	Racemization in Reverse: Evidence that D-Amino Acid Toxicity on Earth Is Controlled by Bacteria with Racemases
作者:	Gaosen Zhang; Henry J. Sun
刊名:	PLOS ONE
ISSN:	1932-6203
出版年:	2014
发表日期:	2014-3-19
卷:	9, 期:3
语种:	英语
英文关键词:	Alanine ; Deserts ; Enantiomers ; Arthrobacter ; Detoxification ; Operons ; Wetlands ; Cell walls
英文摘要:	D-amino acids are toxic for life on Earth. Yet, they form constantly due to geochemical racemization and bacterial growth (the cell walls of which contain D-amino acids), raising the fundamental question of how they ultimately are recycled. This study provides evidence that bacteria use D-amino acids as a source of nitrogen by running enzymatic racemization in reverse. Consequently, when soils are inundated with racemic amino acids, resident bacteria consume D- as well as L-enantiomers, either simultaneously or sequentially depending on the level of their racemase activity. Bacteria thus protect life on Earth by keeping environments D-amino acid free.
URL:	http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0092101&type=printable
Citation statistics:
资源类型:	期刊论文
标识符:	http://119.78.100.158/handle/2HF3EXSE/20066
Appears in Collections:	过去全球变化的重建影响、适应和脆弱性科学计划与规划气候变化与战略全球变化的国际研究计划气候减缓与适应气候变化事实与影响

Files in This Item:

File Name/ File Size	Content Type	Version	Access	License
journal.pone.0092101.PDF（1497KB）	期刊论文	作者接受稿	开放获取	CC BY-NC-SA	View Download

作者单位:

Division of Earth and Ecosystem Sciences, Desert Research Institute, Las Vegas, Nevada, United States of America;Division of Earth and Ecosystem Sciences, Desert Research Institute, Las Vegas, Nevada, United States of America

Recommended Citation:

Gaosen Zhang,Henry J. Sun. Racemization in Reverse: Evidence that D-Amino Acid Toxicity on Earth Is Controlled by Bacteria with Racemases[J]. PLOS ONE,2014-01-01,9(3)

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