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DOI:	10.1371/journal.pone.0120730
论文题名:	Clostridium difficile Infection Seasonality: Patterns across Hemispheres and Continents – A Systematic Review
作者:	Luis Furuya-Kanamori; Samantha J. McKenzie; Laith Yakob; Justin Clark; David L. Paterson; Thomas V. Riley; Archie C. Clements
刊名:	PLOS ONE
ISSN:	1932-6203
出版年:	2015
发表日期:	2015-3-16
卷:	10, 期:3
语种:	英语
英文关键词:	Southern Hemisphere ; Antibiotics ; Northern Hemisphere ; Clostridium difficile ; Nosocomial infections ; Seasons ; Database searching ; Respiratory infections
英文摘要:	Background Studies have demonstrated seasonal variability in rates of Clostridium difficile infection (CDI). Synthesising all available information on seasonality is a necessary step in identifying large-scale epidemiological patterns and elucidating underlying causes. Methods Three medical and life sciences publication databases were searched from inception to October 2014 for longitudinal epidemiological studies written in English, Spanish or Portuguese that reported the incidence of CDI. The monthly frequency of CDI were extracted, standardized and weighted according to the number of follow-up months. Cross correlation coefficients (XCORR) were calculated to examine the correlation and lag between the year-month frequencies of reported CDI across hemispheres and continents. Results The search identified 13, 5 and 2 studies from North America, Europe, and Oceania, respectively that met the inclusion criteria. CDI had a similar seasonal pattern in the Northern and Southern Hemisphere characterized by a peak in spring and lower frequencies of CDI in summer/autumn with a lag of 8 months (XCORR = 0.60) between hemispheres. There was no difference between the seasonal patterns across European and North American countries. Conclusion CDI demonstrates a distinct seasonal pattern that is consistent across North America, Europe and Oceania. Further studies are required to identify the driving factors of the observed seasonality.
URL:	http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0120730&type=printable
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资源类型:	期刊论文
标识符:	http://119.78.100.158/handle/2HF3EXSE/20456
Appears in Collections:	过去全球变化的重建影响、适应和脆弱性科学计划与规划气候变化与战略全球变化的国际研究计划气候减缓与适应气候变化事实与影响

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File Name/ File Size	Content Type	Version	Access	License
journal.pone.0120730.PDF（1342KB）	期刊论文	作者接受稿	开放获取	CC BY-NC-SA	View Download

作者单位:

Research School of Population Health, The Australian National University, Canberra, Australian Capital Territory, Australia;School of Population Health, The University of Queensland, Herston, Queensland, Australia;London School of Hygiene and Tropical Medicine, Department of Disease Control, London, United Kingdom;Drug ARM Australasia, Annerley, Queensland, Australia;The University of Queensland, UQ Centre for Clinical Research, Herston, Queensland, Australia;Microbiology & Immunology, The University of Western Australia and Department of Microbiology PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Nedlands, Western Australia, Australia;Research School of Population Health, The Australian National University, Canberra, Australian Capital Territory, Australia

Recommended Citation:

Luis Furuya-Kanamori,Samantha J. McKenzie,Laith Yakob,et al. Clostridium difficile Infection Seasonality: Patterns across Hemispheres and Continents – A Systematic Review[J]. PLOS ONE,2015-01-01,10(3)

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