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globalchange > 过去全球变化的重建

DOI:	10.1371/journal.pone.0121846
论文题名:	Global Spectrum of Copy Number Variations Reveals Genome Organizational Plasticity and Proposes New Migration Routes
作者:	Avinash M. Veerappa; Sangeetha Vishweswaraiah; Kusuma Lingaiah; Megha Murthy; Raviraj V. Suresh; Dinesh S. Manjegowda; Nallur B. Ramachandra
刊名:	PLOS ONE
ISSN:	1932-6203
出版年:	2015
发表日期:	2015-4-24
卷:	10, 期:4
语种:	英语
英文关键词:	Genome analysis ; Africa ; Comparative genomics ; Human mobility ; India ; China ; Copy number variation ; Jews
英文摘要:	Global spectrum of CNVs is required to catalog variations to provide a high-resolution on the dynamics of genome-organization and human migration. In this study, we performed genome-wide genotyping using high-resolution arrays and identified 44,109 CNVs from 1,715 genomes across 12 populations. The study unraveled the force of independent evolutionary dynamics on genome-organizational plasticity across populations. We demonstrated the use of CNV tool to study human migration and identified a second major settlement establishing new migration routes in addition to existing ones.
URL:	http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0121846&type=printable
Citation statistics:
资源类型:	期刊论文
标识符:	http://119.78.100.158/handle/2HF3EXSE/21324
Appears in Collections:	过去全球变化的重建影响、适应和脆弱性科学计划与规划气候变化与战略全球变化的国际研究计划气候减缓与适应气候变化事实与影响

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File Name/ File Size	Content Type	Version	Access	License
journal.pone.0121846.PDF（5014KB）	期刊论文	作者接受稿	开放获取	CC BY-NC-SA	View Download

作者单位:

Genetics and Genomics Lab, Department of Studies in Zoology, University of Mysore, Manasagangotri, Mysore-06, Karnataka, India;Genetics and Genomics Lab, Department of Studies in Zoology, University of Mysore, Manasagangotri, Mysore-06, Karnataka, India;Genetics and Genomics Lab, Department of Studies in Zoology, University of Mysore, Manasagangotri, Mysore-06, Karnataka, India;Genetics and Genomics Lab, Department of Studies in Zoology, University of Mysore, Manasagangotri, Mysore-06, Karnataka, India;Genetics and Genomics Lab, Department of Studies in Zoology, University of Mysore, Manasagangotri, Mysore-06, Karnataka, India;NUCSER, KS Hegde Medical Academy, Nitte University, Mangalore-18, Karnataka, India;Genetics and Genomics Lab, Department of Studies in Zoology, University of Mysore, Manasagangotri, Mysore-06, Karnataka, India

Recommended Citation:

Avinash M. Veerappa,Sangeetha Vishweswaraiah,Kusuma Lingaiah,et al. Global Spectrum of Copy Number Variations Reveals Genome Organizational Plasticity and Proposes New Migration Routes[J]. PLOS ONE,2015-01-01,10(4)

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