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DOI:	10.1371/journal.pone.0136881
论文题名:	Mammographic Breast Density in Chinese Women: Spatial Distribution and Autocorrelation Patterns
作者:	Christopher W. K. Lai; Helen K. W. Law
刊名:	PLOS ONE
ISSN:	1932-6203
出版年:	2015
发表日期:	2015-9-2
卷:	10, 期:9
语种:	英语
英文关键词:	Chinese people ; Computer software ; Spatial autocorrelation ; Tissue distribution ; Bone density ; Breast cancer ; Cancer risk factors ; Health services research
英文摘要:	Mammographic breast density (MBD) is a strong risk factor for breast cancer. The spatial distribution of MBD in the breast is variable and dependent on physiological, genetic, environmental and pathological factors. This pilot study aims to define the spatial distribution and autocorrelation patterns of MBD in Chinese women aged 40–60. By analyzing their digital mammographic images using a public domain Java image processing program for segmentation and quantification of MBD, we found their left and right breasts were symmetric to each other in regard to their breast size (Total Breast Area), the amount of BMD (overall PD) and Moran's I values. Their MBD was also spatially autocorrelated together in the anterior part of the breast in those with a smaller breast size, while those with a larger breast size tend to have their MBD clustered near the posterior part of the breast. Finally, we observed that the autocorrelation pattern of MBD was dispersed after a 3-year observation period.
URL:	http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0136881&type=printable
Citation statistics:
资源类型:	期刊论文
标识符:	http://119.78.100.158/handle/2HF3EXSE/22685
Appears in Collections:	过去全球变化的重建影响、适应和脆弱性科学计划与规划气候变化与战略全球变化的国际研究计划气候减缓与适应气候变化事实与影响

Files in This Item:

File Name/ File Size	Content Type	Version	Access	License
journal.pone.0136881.PDF（1992KB）	期刊论文	作者接受稿	开放获取	CC BY-NC-SA	View Download

作者单位:

Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, HKSAR, China;Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, HKSAR, China

Recommended Citation:

Christopher W. K. Lai,Helen K. W. Law. Mammographic Breast Density in Chinese Women: Spatial Distribution and Autocorrelation Patterns[J]. PLOS ONE,2015-01-01,10(9)

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