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globalchange > 过去全球变化的重建

DOI:	10.1371/journal.pone.0167972
论文题名:	Osmoregulated Chloride Currents in Hemocytes from Mytilus galloprovincialis
作者:	Monica Bregante; Armando Carpaneto; Veronica Piazza; Francesca Sbrana; Massimo Vassalli; Marco Faimali; Franco Gambale
刊名:	PLOS ONE
ISSN:	1932-6203
出版年:	2016
发表日期:	2016-12-9
卷:	11, 期:12
语种:	英语
英文关键词:	Chlorides ; Hemocytes ; Membrane potential ; Zinc ; Osmotic pressure ; Pipettes ; Bivalves ; Sea water
英文摘要:	We investigated the biophysical properties of the transport mediated by ion channels in hemocytes from the hemolymph of the bivalve Mytilus galloprovincialis. Besides other transporters, mytilus hemocytes possess a specialized channel sensitive to the osmotic pressure with functional properties similar to those of other transport proteins present in vertebrates. As chloride fluxes may play an important role in the regulation of cell volume in case of modifications of the ionic composition of the external medium, we focused our attention on an inwardly-rectifying voltage-dependent, chloride-selective channel activated by negative membrane potentials and potentiated by the low osmolality of the external solution. The chloride channel was slightly inhibited by micromolar concentrations of zinc chloride in the bath solution, while the antifouling agent zinc pyrithione did not affect the channel conductance at all. This is the first direct electrophysiological characterization of a functional ion channel in ancestral immunocytes of mytilus, which may bring a contribution to the understanding of the response of bivalves to salt and contaminant stresses.
URL:	http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0167972&type=printable
Citation statistics:
资源类型:	期刊论文
标识符:	http://119.78.100.158/handle/2HF3EXSE/23405
Appears in Collections:	过去全球变化的重建影响、适应和脆弱性科学计划与规划气候变化与战略全球变化的国际研究计划气候减缓与适应气候变化事实与影响

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File Name/ File Size	Content Type	Version	Access	License
journal.pone.0167972.pdf（2567KB）	期刊论文	作者接受稿	开放获取	CC BY-NC-SA	View Download

作者单位:

Institute of Biophysics, National Research Council of Italy (IBF), Genova, Italy;Institute of Biophysics, National Research Council of Italy (IBF), Genova, Italy;Institute of Marine Sciences, National Research Council of Italy (ISMAR), Genova, Italy;Institute of Biophysics, National Research Council of Italy (IBF), Genova, Italy;Institute of Biophysics, National Research Council of Italy (IBF), Genova, Italy;Institute of Marine Sciences, National Research Council of Italy (ISMAR), Genova, Italy;Institute of Biophysics, National Research Council of Italy (IBF), Genova, Italy

Recommended Citation:

Monica Bregante,Armando Carpaneto,Veronica Piazza,et al. Osmoregulated Chloride Currents in Hemocytes from Mytilus galloprovincialis[J]. PLOS ONE,2016-01-01,11(12)

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