| DOI: | 10.2172/1093259
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| 报告号: | DOE-Harvard-62685- Final Report
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| 报告题名: | Effects of Low-Dose Alpha-Particle Irradiation in Human Cells: The Role of Induced Genes and the Bystander Effect. Final Technical Report (9/15/1998-5/31/2005) |
| 作者: | Little, John B.
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| 出版年: | 2013
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| 发表日期: | 2013-09-17
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| 国家: | 美国
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| 语种: | 英语
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| 中文主题词: | 公共健康
; PH
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| 主题词: | PUBLIC HEALTH
; PH
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| 英文摘要: | This grant was designed to examine the cellular and molecular mechanisms for the bystander effect of radiation (initially described in this laboratory) whereby damage signals are passed from irradiated to non-irradiated cells in a population. These signals induce genetic effects including DNA damage, mutations and chromosomal aberrations in the nonirradiated cells. Experiments were carried out in cultured mammalian cells, primarily human diploid cells, irradiated with alpha particles. This research resulted in 17 publications in the refereed literature and is described in the Progress Report where it is keyed to the publication list. This project was initiated at the Harvard School of Public Health (HSPH) and continued in collaboration with students/fellows at Colorado State University (CSU) and the New Jersey Medical School (NJMS). |
| URL: | http://www.osti.gov/scitech/servlets/purl/1093259
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| Citation statistics: |
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| 资源类型: | 研究报告
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| 标识符: | http://119.78.100.158/handle/2HF3EXSE/40991
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| Appears in Collections: | 过去全球变化的重建
影响、适应和脆弱性
科学计划与规划
气候变化与战略
全球变化的国际研究计划
气候减缓与适应
气候变化事实与影响
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| 1093259.pdf（114KB） | 研究报告 | -- | 开放获取 | | View
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| Recommended Citation: | |
Little, John B.. Effects of Low-Dose Alpha-Particle Irradiation in Human Cells: The Role of Induced Genes and the Bystander Effect. Final Technical Report (9/15/1998-5/31/2005). 2013-01-01.
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