| DOI: | 10.2172/1159247
|
| 报告号: | DOE-UIUC-SC5348
|
| 报告题名: | Final Technical Report for Award # ER64999 |
| 作者: | Metcalf, William W.
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| 出版年: | 2014
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| 发表日期: | 2014-10-08
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| 国家: | 美国
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| 语种: | 英语
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| 英文关键词: | methane
; methanogenic archaea
; systems biology
; genomics
; transcriptomics
; metabolic modelling
|
| 中文主题词: | 碳
; 甲烷
|
| 主题词: | CARBON
; METHANE
|
| 英文摘要: | This report provides a summary of activities for Award # ER64999, a Genomes to Life Project funded by the Office of Science, Basic Energy Research. The project was entitled "Methanogenic archaea and the global carbon cycle: a systems biology approach to the study of Methanosarcina species". The long-term goal of this multi-investigator project was the creation of integrated, multiscale models that accurately and quantitatively predict the role of Methanosarcina species in the global carbon cycle under dynamic environmental conditions. To achieve these goals we pursed four specific aims: (1) genome sequencing of numerous members of the Order Methanosarcinales, (2) identification of genomic sources of phenotypic variation through in silico comparative genomics, (3) elucidation of the transcriptional networks of two Methanosarcina species, and (4) development of comprehensive metabolic network models for characterized strains to address the question of how metabolic models scale with genetic distance. |
| URL: | http://www.osti.gov/scitech/servlets/purl/1159247
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| Citation statistics: |
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| 资源类型: | 研究报告
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| 标识符: | http://119.78.100.158/handle/2HF3EXSE/41393
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| Appears in Collections: | 过去全球变化的重建
影响、适应和脆弱性
科学计划与规划
气候变化与战略
全球变化的国际研究计划
气候减缓与适应
气候变化事实与影响
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Version |
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| 1159247.doc（117KB） | 研究报告 | -- | 开放获取 | | View
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作者单位: | University of Illinois
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| Recommended Citation: | |
Metcalf, William W.. Final Technical Report for Award # ER64999. 2014-01-01.
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