DOI: 10.1016/j.tree.2016.09.005
论文题名: Understanding Inbreeding Depression, Purging, and Genetic Rescue
作者: Hedrick P.W. ; Garcia-Dorado A.
刊名: Trends in Ecology and Evolution
ISSN: 1695347
出版年: 2016
卷: 31, 期: 12 起始页码: 940
结束页码: 952
语种: 英语
英文关键词: genetic drift
; genetic rescue
; inbreeding
; mutation
; purging
Scopus关键词: extinction risk
; fitness
; genetic drift
; genetic resource
; genetic structure
; genomics
; inbreeding depression
; mutation
; survival
英文摘要: Inbreeding depression, the reduction of fitness caused by inbreeding, is a nearly universal phenomenon that depends on past mutation, selection, and genetic drift. Recent estimates suggest that its impact on individual fitness is even greater than previously thought. Genomic information is contributing to its detection and can enlighten important aspects of its genetic architecture. In natural populations, purging and genetic rescue mitigate fitness decline during inbreeding periods, and might be critical to population survival, thus, both mechanisms should be considered when assessing extinction risks. However, deliberate purging and genetic rescue involve considerable risk in the short and medium term, so that neither appears to be a panacea against high inbreeding depression. © 2016 Elsevier Ltd
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资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/66980
Appears in Collections: 全球变化的国际研究计划 气候变化与战略
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作者单位: School of Life Sciences, Arizona State University, Tempe, AZ, United States; Departamento de Genética, Facultad de Biología, Universidad Complutense, Madrid, Spain
Recommended Citation:
Hedrick P.W.,Garcia-Dorado A.. Understanding Inbreeding Depression, Purging, and Genetic Rescue[J]. Trends in Ecology and Evolution,2016-01-01,31(12)