DOI: 10.1016/j.tree.2014.09.002
论文题名: Unifying external and internal immune defences
作者: Otti O. ; Tragust S. ; Feldhaar H.
刊名: Trends in Ecology and Evolution
ISSN: 1695347
出版年: 2014
卷: 29, 期: 11 起始页码: 625
结束页码: 634
语种: 英语
英文关键词: Antimicrobial peptides
; Ecological immunology
; Immune defence strategies
; Symbionts
; Venom
Scopus关键词: antimicrobial activity
; host-pathogen interaction
; host-symbiont interaction
; immune system
; immunity
; physiology
; trade-off
; venom
; anti-infective agents
; animals
; biological evolution
; drug effects
; Environment
; Immunity
; immunology
; metabolism
; Microbiota
; physiology
; Symbiosis
; Animals
; Anti-Infective Agents
; Biological Evolution
; Environment
; Immunity
; Microbiota
; Symbiosis
英文摘要: External immune defence, such as antimicrobial secretions, is not generally viewed as part of the immune system. Nevertheless, it constitutes a first barrier to pathogens and manipulates the microbial environment. Hygienic measures from the protection of oneself or conspecifics, of the nesting site, or of stored food might be more efficient with secreted antimicrobials. Here, we argue that antimicrobial secretions represent an extended arm of the immune system, forming an underappreciated selective force in the evolution of immune systems. Integrating external immunity into the immune system and general host physiology provides an amenable concept for the understanding of immune system variation and life-history trade-offs. Future research should evaluate complementary or additive roles of antimicrobial secretions in relation to internal immunity. © 2014 Elsevier Ltd. Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/67329
Appears in Collections: 全球变化的国际研究计划 气候变化与战略
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作者单位: Animal Population Ecology, Animal Ecology I, Bayreuth Center of Ecology and Environmental Research (BayCEER), University of Bayreuth, Universitätsstrasse 30, Bayreuth, Germany
Recommended Citation:
Otti O.,Tragust S.,Feldhaar H.. Unifying external and internal immune defences[J]. Trends in Ecology and Evolution,2014-01-01,29(11)