DOI: 10.1016/j.atmosenv.2014.02.003
Scopus记录号: 2-s2.0-84894239621
论文题名: Effects on heart rate variability by artificially generated indoor nano-sized particles in a chamber study
作者: Hagerman I ; , Isaxon C ; , Gudmundsson A ; , Wierzbicka A ; , Dierschke K ; , Berglund M ; , Pagels J ; , Nielsen J ; , Assarsson E ; , Andersson U ; B ; K ; , Xu Y ; , Jönsson B ; A ; G ; , Bohgard M
刊名: Atmospheric Environment
ISSN: 0168-2563
EISSN: 1573-515X
出版年: 2014
卷: 88 起始页码: 165
结束页码: 171
语种: 英语
英文关键词: Airborne particles
; Autonomic control
; Cardiovascular
; HRV
; Nano particles
Scopus学科分类: Environmental Science: Water Science and Technology
; Earth and Planetary Sciences: Earth-Surface Processes
; Environmental Science: Environmental Chemistry
英文摘要: Background: Airborne particles are associated with increased morbidity and mortality due to respiratory and cardiovascular diseases in polluted areas. There is a growing interest in nano-sized particles with diameter <100nm and their potential health effects. Heart rate variability (HRV) is a noninvasive method for cardiovascular risk prediction in high prevalent groups. Aim of study: The aim was to evaluate the impact of nano-sized indoor air particles on HRV for healthy and adult females. Methods: All exposures were performed as controlled chamber experiments with particle exposure from burning candles, terpene+ozone reactions or filtered air in a double-blind cross over design. Twenty-two healthy females were investigated during 10min periods at different exposures and the reactivity in high frequency (HF) spectral band of HRV were computed. Results: Heart rate was unchanged from baseline values in all groups during all experimental settings. HF power of HRV tended to increase during exposure to particles from burning candle while particles from terpene+ozone reactions tended to decrease HF power. Conclusions: Exposure to nano-sized particles of burning candles or terpene+ozone reactions results in different patterns of heart rate variability, with signs of altered autonomic cardiovascular control. Practical implications: This study indicates that the HRV method may be used for information on physiological responses of exposure to different nano-sized particles and contribute to the understanding of mechanisms behind health effects of particle exposures. © 2014 The Authors.
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资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/80703
Appears in Collections: 气候变化事实与影响
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作者单位: Department of Cardiology, Karolinska Institute, Karolinska University Hospital, Huddinge, Sweden; Ergonomics and Aerosol Technology, Lund University, Sweden; Division of Occupational and Environmental Medicine, Lund University, Sweden
Recommended Citation:
Hagerman I,, Isaxon C,, Gudmundsson A,et al. Effects on heart rate variability by artificially generated indoor nano-sized particles in a chamber study[J]. Atmospheric Environment,2014-01-01,88