DOI: 10.1016/j.atmosenv.2014.12.060
Scopus记录号: 2-s2.0-84920868011
论文题名: Lung burden and deposition distribution of inhaled atmospheric urban ultrafine particles as the first step in their health risk assessment
作者: Salma I ; , Füri P ; , Németh Z ; , Balásházy I ; , Hofmann W ; , Farkas T
刊名: Atmospheric Environment
ISSN: 0168-2563
EISSN: 1573-515X
出版年: 2015
卷: 104 起始页码: 39
结束页码: 49
语种: 英语
英文关键词: Exposure assessment
; Nanoaerosol
; Respiratory deposition
; Stochastic lung deposition model
; Surface density deposition
Scopus关键词: Biological organs
; Deposition rates
; Health risks
; Risk assessment
; Sleep research
; Stochastic models
; Stochastic systems
; Urban planning
; Deposition distribution
; Differential mobility particle sizer
; Exposure assessment
; Lung depositions
; Nanoaerosol
; Particle number size distribution
; Surface density
; Tracheobronchial region
; Deposition
; aerosol composition
; atmospheric deposition
; atmospheric pollution
; health risk
; particle size
; pollution exposure
; public health
; respiratory disease
; risk assessment
; size distribution
; adult
; aerosol
; airway
; Article
; atmosphere
; breathing exercise
; case report
; density
; female
; health hazard
; human
; humidity
; inhalation
; lung burden
; lung ventilation
; normal human
; particle size
; particulate matter
; physical activity
; priority journal
; sitting
; sleep
; surface property
; urban area
; Budapest
; Hungary
Scopus学科分类: Environmental Science: Water Science and Technology
; Earth and Planetary Sciences: Earth-Surface Processes
; Environmental Science: Environmental Chemistry
英文摘要: Realistic median particle number size distributions were derived by a differential mobility particle sizer in a diameter range of 6-1000nm for near-city background, city centre, street canyon and road tunnel environments in Budapest. Deposition of inhaled particles within airway generations of an adult woman was determined by a stochastic lung deposition model for sleeping, sitting, light and heavy exercise breathing conditions. Deposition fractions in the respiratory tract were considerable and constant for all physical activities with a mean of 56%. Mean deposition fraction in the extra-thoracic region averaged for the urban environments was decreasing monotonically from 26% for sleeping to 9.4% for heavy exercise. The mean deposition fractions in the tracheobronchial region were constant for the physical activities and urban environments with an overall mean of 12.5%, while the mean deposition fraction in the acinar region averaged for the urban locations increased monotonically with physical activity from 14.7% for sleeping to 34% for heavy exercise. The largest contribution of the acinar deposition to the lung deposition was 75%. The deposition rates in the lung were larger than in the extra-thoracic region, and the deposition rate in the lung was increasingly realised in the AC region by physical activity. It was the extra-thoracic region that received the largest surface density deposition rates; its loading was higher by 3 orders of magnitude than for the lung. Deposition fractions in the airway generations exhibited a distinct peak in the acinar region. The maximum of the curves was shifted to peripheral airway generations with physical activity. The shapes of the surface density deposition rate curves were completely different from those for the deposition rates, indicating that the first few airway generations received the highest surface loading in the lung. © 2014 Elsevier Ltd. Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/81976
Appears in Collections: 气候变化事实与影响
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作者单位: Institute of Chemistry, Eötvös University, P.O. Box 32, Budapest, Hungary; Centre for Energy Research, Hungarian Academy of Sciences, P.O. Box 49, Budapest, Hungary; Department of Materials Research and Physics, University of Salzburg, Hellbrunnerstr. 34, Salzburg, Austria
Recommended Citation:
Salma I,, Füri P,, Németh Z,et al. Lung burden and deposition distribution of inhaled atmospheric urban ultrafine particles as the first step in their health risk assessment[J]. Atmospheric Environment,2015-01-01,104