DOI: 10.1016/j.atmosenv.2017.05.019
Scopus记录号: 2-s2.0-85020002189
论文题名: Cytotoxic and genotoxic responses of human lung cells to combustion smoke particles of Miscanthus straw, softwood and beech wood chips
作者: Arif A ; T ; , Maschowski C ; , Garra P ; , Garcia-Käufer M ; , Petithory T ; , Trouvé G ; , Dieterlen A ; , Mersch-Sundermann V ; , Khanaqa P ; , Nazarenko I ; , Gminski R ; , Gieré R
刊名: Atmospheric Environment
ISSN: 0168-2563
EISSN: 1573-515X
出版年: 2017
卷: 163 起始页码: 138
结束页码: 154
语种: 英语
英文关键词: Biomass combustion
; Miscanthus straw
; PM0.4-1 emissions
; Polycyclic aromatic hydrocarbons (PAHs)
; Toxicity
; Wood chips
Scopus关键词: Alkalinity
; Aromatic compounds
; Aromatic hydrocarbons
; Biological organs
; Biomass
; Cytotoxicity
; Efficiency
; Fly ash
; Heavy metals
; Hydrocarbons
; Particulate emissions
; Polycyclic aromatic hydrocarbons
; Softwoods
; Toxicity
; Wood products
; Biomass combustion
; Combustion efficiencies
; Incomplete combustion
; Miscanthus
; Polycyclic aromatic hydrocarbons (PAHS)
; Reflection microscope
; Residual water content
; Wood chip
; Combustion
; polycyclic aromatic hydrocarbon
; biofuel
; biomass
; cardiovascular disease
; cells and cell components
; combustion
; emission
; genotoxicity
; grass
; PAH
; particulate matter
; respiratory disease
; smoke
; software
; straw
; toxicity
; wood
; A-549 cell line
; apoptosis assay
; Article
; BEAS 2B cell line
; beech
; boiler
; cardiovascular disease
; cell viability
; combustion
; comet assay
; confocal microscopy
; cytotoxicity
; DNA damage
; genotoxicity
; human
; human cell
; inhalation
; lung alveolus cell
; lung alveolus epithelium cell
; lung cell line
; lung disease
; mass spectrometry
; miscanthus straw
; nonhuman
; particle size
; particulate matter
; photon correlation spectroscopy
; plant product
; priority journal
; scanning electron microscopy
; softwood chip
; straw
; surface area
; transmission electron microscopy
; water content
; wood chip
; WST-1 assay
; X ray diffraction
; Biomass
; Chips
; Combustion
; Toxicity
; Fagus
; Miscanthus
Scopus学科分类: Environmental Science: Water Science and Technology
; Earth and Planetary Sciences: Earth-Surface Processes
; Environmental Science: Environmental Chemistry
英文摘要: Inhalation of particulate matter (PM) from residential biomass combustion is epidemiologically associated with cardiovascular and pulmonary diseases. This study investigates PM0.4-1 emissions from combustion of commercial Miscanthus straw (MS), softwood chips (SWC) and beech wood chips (BWC) in a domestic-scale boiler (40 kW). The PM0.4-1 emitted during combustion of the MS, SWC and BWC were characterized by ICP-MS/OES, XRD, SEM, TEM, and DLS. Cytotoxicity and genotoxicity in human alveolar epithelial A549 and human bronchial epithelial BEAS-2B cells were assessed by the WST-1 assay and the DNA-Alkaline Unwinding Assay (DAUA). PM0.4-1 uptake/translocation in cells was investigated with a new method developed using a confocal reflection microscope. SWC and BWC had a inherently higher residual water content than MS. The PM0.4-1 emitted during combustion of SWC and BWC exhibited higher levels of Polycyclic Aromatic Hydrocarbons (PAHs), a greater variety of mineral species and a higher heavy metal content than PM0.4-1 from MS combustion. Exposure to PM0.4-1 from combustion of SWC and BWC induced cytotoxic and genotoxic effects in human alveolar and bronchial cells, whereby the strongest effect was observed for BWC and was comparable to that caused by diesel PM (SRM 2 975), In contrast, PM0.4-1 from MS combustion did not induce cellular responses in the studied lung cells. A high PAH content in PM emissions seems to be a reliable chemical marker of both combustion efficiency and particle toxicity. Residual biomass water content strongly affects particulate emissions and their toxic potential. Therefore, to minimize the harmful effects of fine PM on health, improvement of combustion efficiency (aiming to reduce the presence of incomplete combustion products bound to PM) and application of fly ash capture technology, as well as use of novel biomass fuels like Miscanthus straw is recommended. © 2017 Elsevier Ltd Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/82496
Appears in Collections: 气候变化事实与影响
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作者单位: Institute of Environmental Health Sciences and Hospital Infection Control, University Medical Center Freiburg, Faculty of Medicine, Freiburg, Germany; Sulaimani Polytechnic University (SPU) and Kurdistan Institution for Strategic Studies and Scientific Research (KISSR), Qirga - Sulaimani, Iraq; Laboratoire Gestion des Risques et Environnement (LGRE), Université de Haute-Alsace, Mulhouse Cedex, France; Laboratoire Modélisation Intelligence des Procédés et des Systèmes (MIPS), Université de Haute-Alsace, Mulhouse Cedex, France; Institut de Sciences des Materiaux de Mulhouse, CNRS UMR7361, Universite de Haute-Alsace, 15 rue Jean Starcky, Mulhouse, France; Department of Earth and Environmental Science and Center of Excellence in Environmental Toxicology, University of Pennsylvania, Philadelphia, PA, United States; Institute of Earth and Environmental Sciences-Geochemistry, University of Freiburg, Freiburg, Germany
Recommended Citation:
Arif A,T,, Maschowski C,et al. Cytotoxic and genotoxic responses of human lung cells to combustion smoke particles of Miscanthus straw, softwood and beech wood chips[J]. Atmospheric Environment,2017-01-01,163