DOI: 10.1016/j.marpolbul.2014.01.040
Scopus记录号: 2-s2.0-84906222552
论文题名: Comparative embryotoxicity of phenanthrene and alkyl-phenanthrene to marine medaka (Oryzias melastigma)
作者: Mu J. ; Wang J. ; Jin F. ; Wang X. ; Hong H.
刊名: Marine Pollution Bulletin
ISSN: 0025-326X
EISSN: 1879-3363
出版年: 2014
卷: 85, 期: 2 起始页码: 505
结束页码: 515
语种: 英语
英文关键词: Alkyl-PAHs
; Blue sac disease
; Early life stage
; Marine oil spill
; Metabolites
Scopus关键词: Cardiovascular system
; Metabolites
; Oil spills
; Risk assessment
; Toxicity
; Alkyl-PAHs
; Blue sac disease
; Comparative studies
; Early life
; Ecological risk assessment
; Freshwater fishes
; Marine oil spills
; Oryzias melastigma
; Anthracene
; 7 isopropyl 1 methylphenanthrene
; alkyl phenanthrene
; cytochrome P450 1A1
; phenanthrene
; tricyclic aromatic compound
; unclassified drug
; phenanthrene
; phenanthrene derivative
; retene
; water pollutant
; ecotoxicology
; embryo
; finfish
; metabolite
; oil spill
; PAH
; phenanthrene
; risk assessment
; toxicity
; article
; comparative study
; developmental stage
; developmental toxicity
; embryo development
; embryotoxicity
; environmental exposure
; enzyme activity
; freshwater fish
; larva
; nonhuman
; Oryzias
; Oryzias melastigma
; pericardial edema
; protein expression
; stretched heart
; toxicity testing
; yolk sac edema
; animal
; drug effects
; embryology
; metabolism
; oil spill
; Oryzias
; risk assessment
; toxicity
; water pollutant
; Oryzias melastigma
; Oryziinae
; Pisces
; Animals
; Larva
; Oryzias
; Petroleum Pollution
; Phenanthrenes
; Risk Assessment
; Water Pollutants, Chemical
Scopus学科分类: Agricultural and Biological Sciences: Aquatic Science
; Earth and Planetary Sciences: Oceanography
; Environmental Science: Pollution
英文摘要: Alkylated polycyclic aromatic hydrocarbons (alkyl-PAHs) are the predominant form of PAHs in oil, comprising 85-95% of total PAHs. However, little attention has been paid to these chemicals in ecological risk assessment of marine oil spill. A comparative study of the toxic effects of phenanthrene and retene (7-isopropyl-1-methylphenanthrene, an alkyl-phenanthrene) on the early life stage of marine medaka (Oryzias melastigma) was conducted. Results showed that retene was significantly more toxic than phenanthrene, and marine medaka could be more sensitive to retene than some freshwater fishes. Retene had a higher excretion rate than phenanthrene during the larvae stage. Both of compounds resulted in developmental malformation of marine medaka embryos, with phenanthrene affecting on peripheral vascular system and yolk sac, while retene affecting on cardiac tissues. The toxicity of phenanthrene might be mainly related to its anesthetic effects, and that of retene might be related to the CYP1A-mediated toxicity of its metabolites. © 2014 Elsevier Ltd. Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/85301
Appears in Collections: 过去全球变化的重建 全球变化的国际研究计划
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作者单位: Key Laboratory for Ecological Environment in Coastal Areas, State Oceanic Administration, Dalian 116023, China; Division of Marine Chemistry, National Marine Environmental Monitoring Center, Dalian 116023, China; State Key Laboratory of Marine Environmental Science, Environmental Science Research Center, Xiamen University, Xiamen 361005, China; No. 42 Linghe Street, Shahekou District, Dalian 116023, China; No. 182 Daxue Road, Siming District, Xiamen 361005, China
Recommended Citation:
Mu J.,Wang J.,Jin F.,et al. Comparative embryotoxicity of phenanthrene and alkyl-phenanthrene to marine medaka (Oryzias melastigma)[J]. Marine Pollution Bulletin,2014-01-01,85(2)