DOI: 10.1016/j.marpolbul.2014.04.005
Scopus记录号: 2-s2.0-84906234271
论文题名: Whole genome data for omics-based research on the self-fertilizing fish Kryptolebias marmoratus
作者: Rhee J.-S. ; Lee J.-S.
刊名: Marine Pollution Bulletin
ISSN: 0025-326X
EISSN: 1879-3363
出版年: 2014
卷: 85, 期: 2 起始页码: 532
结束页码: 541
语种: 英语
英文关键词: Genome
; Hermaphroditic fish
; Kryptolebias marmoratus
; Omics
Scopus关键词: Bioinformatics
; Biology
; Fish
; Biological functions
; Developmental biology
; Environmental science
; Genomic information
; Kryptolebias marmoratus
; Mechanistic studies
; Omics
; Zebrafish danio rerio
; Genes
; autogamy
; bioinformatics
; estuarine environment
; fish
; genome
; genomics
; hermaphrodite
; marine environment
; model test
; proteomics
; research work
; article
; bioinformatics
; environmental change
; genome
; genomics
; killifish
; Kryptolebias marmoratus
; medical research
; metabolite
; metabolome
; metabolomics
; molecular genetics
; nonhuman
; osmosis
; oxygen concentration
; phenotypic plasticity
; protein analysis
; proteomics
; sex determination process
; sex differentiation
; sexual maturation
; steroidogenesis
; temperature
; animal
; ecotoxicology
; genetic association
; genetics
; genomics
; hermaphrodite
; killifish
; marine biology
; metabolomics
; procedures
; proteomics
; Cyprinodontoidei
; Danio rerio
; Kryptolebias marmoratus
; Oryzias latipes
; Vertebrata
; Animals
; Ecotoxicology
; Genome
; Genome-Wide Association Study
; Genomics
; Hermaphroditic Organisms
; Killifishes
; Marine Biology
; Metabolomics
; Proteomics
Scopus学科分类: Agricultural and Biological Sciences: Aquatic Science
; Earth and Planetary Sciences: Oceanography
; Environmental Science: Pollution
英文摘要: Genome resources have advantages for understanding diverse areas such as biological patterns and functioning of organisms. Omics platforms are useful approaches for the study of organs and organisms. These approaches can be powerful screening tools for whole genome, proteome, and metabolome profiling, and can be used to understand molecular changes in response to internal and external stimuli. This methodology has been applied successfully in freshwater model fish such as the zebrafish Danio rerio and the Japanese medaka Oryzias latipes in research areas such as basic physiology, developmental biology, genetics, and environmental biology. However, information is still scarce about model fish that inhabit brackish water or seawater. To develop the self-fertilizing killifish Kryptolebias marmoratus as a potential model species with unique characteristics and research merits, we obtained genomic information about K. marmoratus. We address ways to use these data for genome-based molecular mechanistic studies. We review the current state of genome information on K. marmoratus to initiate omics approaches. We evaluate the potential applications of integrated omics platforms for future studies in environmental science, developmental biology, and biomedical research. We conclude that information about the K. marmoratus genome will provide a better understanding of the molecular functions of genes, proteins, and metabolites that are involved in the biological functions of this species. Omics platforms, particularly combined technologies that make effective use of bioinformatics, will provide powerful tools for hypothesis-driven investigations and discovery-driven discussions on diverse aspects of this species and on fish and vertebrates in general. © 2014 Elsevier Ltd. Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/85340
Appears in Collections: 过去全球变化的重建 全球变化的国际研究计划
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作者单位: Department of Marine Science, College of Natural Science, Incheon National University, Incheon 406-772, South Korea; Department of Biological Sciences, College of Science, Sungkyunkwan University, Suwon 440-746, South Korea
Recommended Citation:
Rhee J.-S.,Lee J.-S.. Whole genome data for omics-based research on the self-fertilizing fish Kryptolebias marmoratus[J]. Marine Pollution Bulletin,2014-01-01,85(2)