DOI: 10.1016/j.marpolbul.2014.09.027
Scopus记录号: 2-s2.0-84908659471
论文题名: Indole derivatives inhibited the formation of bacterial biofilm and modulated Ca2+ efflux in diatom
作者: Yang C. ; Yu Y. ; Sun W. ; Xia C.
刊名: Marine Pollution Bulletin
ISSN: 0025-326X
EISSN: 1879-3363
出版年: 2014
卷: 88, 期: 2018-01-02 起始页码: 62
结束页码: 69
语种: 英语
英文关键词: Biofilm
; Biofouling
; Ca2+ flux
; Diatom
; Indole derivatives
Scopus关键词: Biofouling
; Bacterial biofilm
; Diatom
; Indole derivatives
; Biofilms
; 5 bromoindole
; 6 chloroindole
; 6 chlorooxindole
; antifouling agent
; calcium ion
; gramine
; indole
; indole derivative
; unclassified drug
; 6-chloroindole
; antiinfective agent
; calcium
; indole derivative
; biofilm
; biofouling
; concentration (composition)
; diatom
; growth rate
; growth response
; inhibition
; inhibitor
; marine technology
; alga
; algal growth
; Article
; bacterial cell
; bacterial growth
; biofilm
; calcium transport
; cell structure
; controlled study
; Cylindrotheca
; diatom
; minimum inhibitory concentration
; nonhuman
; bacterium
; biofilm
; biofouling
; drug effects
; growth, development and aging
; metabolism
; microbial sensitivity test
; prevention and control
; Bacillariophyta
; Bacteria (microorganisms)
; Anti-Bacterial Agents
; Bacteria
; Biofilms
; Biofouling
; Calcium
; Diatoms
; Indoles
; Microbial Sensitivity Tests
Scopus学科分类: Agricultural and Biological Sciences: Aquatic Science
; Earth and Planetary Sciences: Oceanography
; Environmental Science: Pollution
英文摘要: Marine biofouling is a serious environmental problem worldwide. As an effort to find environmental friendly antifoulants, indole derivatives were determined for their activities to inhibit the growth of bacteria and diatom. The minimum inhibitory concentrations (MICs) of indole derivatives against bacteria were very low, especially for 6-chloroindole. It was proved that 6-chloroindole obviously inhibited the growth of bacteria, interfered with the formation of bacterial biofilm, destroyed bacterial cell morphology and also inhibited the growth of diatom Cylindrotheca sp. as well. By using noninvasive micro-test technique (NMT), 6-chloroindole triggered algal cellular Ca2+ efflux. The highest value was 72.03pmolcm-2s-1, 10.6 times of the control group. The present studies indicated that indole derivatives might have the potential to be new antifouling agents because of their excellent antibacterial and anti-algal activities. At the same time, Ca2+ efflux might be one of the mechanisms that indole derivatives inhibited the growth of diatom. © 2014 Elsevier Ltd. Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/85718
Appears in Collections: 过去全球变化的重建 全球变化的国际研究计划
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作者单位: Key Laboratory of Coastal Biology and Biological Research Utilization, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai, China; School of Ocean, Yantai University, Yantai, China
Recommended Citation:
Yang C.,Yu Y.,Sun W.,et al. Indole derivatives inhibited the formation of bacterial biofilm and modulated Ca2+ efflux in diatom[J]. Marine Pollution Bulletin,2014-01-01,88(2018-01-02)