DOI: 10.1016/j.marpolbul.2015.02.019
Scopus记录号: 2-s2.0-84930756680
论文题名: Intersex related gene expression profiles in clams Scrobicularia plana: Molecular markers and environmental application
作者: Ciocan C.M. ; Cubero-Leon E. ; Langston W.J. ; Pope N. ; Cornelius K. ; Hill E.M. ; Alvarez-Munoz D. ; Indiveri P. ; Lerebours A. ; Minier C. ; Rotchell J.M.
刊名: Marine Pollution Bulletin
ISSN: 0025-326X
EISSN: 1879-3363
出版年: 2015
卷: 95, 期: 2 起始页码: 610
结束页码: 617
语种: 英语
英文关键词: Clams
; English Channel
; Gene expression
; Intersex
Scopus关键词: Cell proliferation
; Genes
; Impurities
; Molluscs
; Shellfish
; Clams
; Cytochrome c oxidase
; English channel
; Environmental applications
; Environmental surveys
; Gene expression profiles
; Intersex
; Proliferating cell nuclear antigens
; Gene expression
; cycline
; cytochrome b
; ferritin
; molecular marker
; biological marker
; transcriptome
; water pollutant
; biomarker
; bivalve
; gene expression
; genetic marker
; intersex
; pollutant
; animal tissue
; Article
; clam
; coastal waters
; controlled study
; cytochrome B gene
; cytochrome c oxidase 1 gene
; female
; ferritin gene
; gene
; gene expression
; genetic transcription
; intersex
; male
; nonhuman
; proliferating cell nuclear antigen gene
; RACK gene
; Scrobicularia plana
; testicular haploid expressed gene
; water contamination
; analysis
; animal
; bivalve
; disorder of sex development
; drug effects
; environment
; environmental monitoring
; gene expression
; genetics
; human
; metabolism
; physiology
; procedures
; testis
; toxicity
; water pollutant
; English Channel
; United Kingdom
; Bivalvia
; Mollusca
; Scrobicularia plana
; Animals
; Biomarkers
; Bivalvia
; Disorders of Sex Development
; Environment
; Environmental Monitoring
; Female
; Gene Expression
; Humans
; Male
; Testis
; Transcriptome
; Water Pollutants, Chemical
Scopus学科分类: Agricultural and Biological Sciences: Aquatic Science
; Earth and Planetary Sciences: Oceanography
; Environmental Science: Pollution
英文摘要: Intersex, the appearance of female characteristics in male gonads, has been identified in several aquatic species. It is a widespread phenomenon in populations of the bivalve, Scrobicularia plana, from the southwest coast of the U.K. Genes previously identified as differentially expressed (. ferritin, testicular haploid expressed gene, THEG, proliferating cell nuclear antigen, PCNA; receptor activated protein kinase C, RACK; cytochrome B, CYB; and cytochrome c oxidase 1, COX1) in intersex clams relative to normal male clams, were selected for characterisation and an environmental survey of the Channel region. Transcripts were significantly differentially expressed at sites with varying intersex incidence and contaminant burdens. Significant correlations between specific gene expressions, key contaminants and sampling locations have been identified, though no single gene was associated with intersex incidence. The results highlight the difficulty in understanding the intersex phenomenon in molluscs where there is still a lack of knowledge on the control of normal reproduction. © 2015 Elsevier Ltd. Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/86037
Appears in Collections: 过去全球变化的重建 全球变化的国际研究计划
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作者单位: School of Pharmacy and Biomolecular Sciences, University of Brighton, Lewes Road, Brighton, United Kingdom; Laboratoire d'Ecotoxicologie, Universite du Havre, 25 Rue Philippe Lebon, BP540, Le Havre, France; Marine Biological Association, The Laboratory, Citadel Hill, Plymouth, United Kingdom; School of Life Sciences, University of Sussex, Falmer, Brighton, United Kingdom; School of Biological, Biomedical and Environmental Sciences, University of Hull, Cottingham Road, Hull, United Kingdom; School of Biological Sciences, Institute of Marine Sciences, University of Portsmouth, Ferry Road, Eastney, Portsmouth, United Kingdom
Recommended Citation:
Ciocan C.M.,Cubero-Leon E.,Langston W.J.,et al. Intersex related gene expression profiles in clams Scrobicularia plana: Molecular markers and environmental application[J]. Marine Pollution Bulletin,2015-01-01,95(2)