DOI: 10.1016/j.marpolbul.2014.10.026
Scopus记录号: 2-s2.0-84930744154
论文题名: Effects of subchronic exposure to glyphosate in juvenile oysters (Crassostrea gigas): FROM molecular to individual levels
作者: Mottier A. ; Séguin A. ; Devos A. ; Pabic C.L. ; Voiseux C. ; Lebel J.M. ; Serpentini A. ; Fievet B. ; Costil K.
刊名: Marine Pollution Bulletin
ISSN: 0025-326X
EISSN: 1879-3363
出版年: 2015
卷: 95, 期: 2 起始页码: 665
结束页码: 677
语种: 英语
英文关键词: Condition index
; Crassostrea gigas
; Enzyme activities
; Gene expression
; Glyphosate
; Histopathology
Scopus关键词: Aquatic ecosystems
; Enzyme activity
; Gene expression
; Genes
; Molluscs
; Shellfish
; Condition index
; Crassostrea gigas
; Defence mechanisms
; Glutathione S-transferases
; Glyphosates
; Histopathology
; Non-target organism
; Subchronic exposure
; Herbicides
; catalase
; glutathione transferase
; glyphosate
; heat shock protein 70
; heat shock protein 90
; malonaldehyde
; messenger RNA
; metallothionein
; glutathione transferase
; glycine
; glyphosate
; herbicide
; malonaldehyde
; metallothionein
; water pollutant
; bivalve
; coastal water
; defense mechanism
; enzyme activity
; gene expression
; glyphosate
; histopathology
; juvenile
; nontarget organism
; pollution effect
; pollution exposure
; animal experiment
; animal tissue
; Article
; concentration (parameters)
; controlled study
; Crassostrea gigas
; environmental exposure
; environmental monitoring
; enzyme activity
; female
; gametogenesis
; gene expression
; gene targeting
; growth rate
; Hsc 72 gene
; Hsp 70 gene
; Hsp 90 gene
; lipid peroxidation
; long term exposure
; male
; marker gene
; nonhuman
; protein content
; quantitative analysis
; survival rate
; xenobiotic metabolism
; yearling
; analogs and derivatives
; animal
; Crassostrea
; metabolism
; physiology
; toxicity
; water pollutant
; Crassostrea gigas
; Ostreidae
; Animals
; Crassostrea
; Gene Expression
; Glutathione Transferase
; Glycine
; Herbicides
; Malondialdehyde
; Metallothionein
; Water Pollutants, Chemical
Scopus学科分类: Agricultural and Biological Sciences: Aquatic Science
; Earth and Planetary Sciences: Oceanography
; Environmental Science: Pollution
英文摘要: Glyphosate-based herbicides are extensively used and can be measured in aquatic ecosystems, including coastal waters. The effect of glyphosate on non-target organisms is an issue of worldwide concern. The aim of this study was to investigate the effects of subchronic exposure to glyphosate in juvenile oysters, Crassostrea gigas. Yearling oysters were exposed to three concentrations of glyphosate (0.1, 1 and 100μgL-1) for 56days. Various endpoints were studied, from the individual level (e.g., gametogenesis and tissue alterations) to the molecular level (mRNA quantification), including biochemical endpoints such as glutathione-S-transferase (GST) and catalase activities and malondialdehyde content. No mortality and growth occurred during the experiment, and individual biomarkers revealed only slight effects. The levels of gene expression significantly increased in oysters exposed to the highest glyphosate concentration (GST and metallothioneins) or to all concentrations (multi-xenobiotic resistance). These results suggested an activation of defence mechanisms at the molecular level. © 2014 Elsevier Ltd. Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/86288
Appears in Collections: 过去全球变化的重建 全球变化的国际研究计划
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作者单位: Normandie Université, Université de Caen Basse-Normandie, Caen, France; UMR BOREA (Biologie des Organismes et des Ecosystèmes Aquatiques), MNHN, UPMC, UCBN, CNRS-7208, IRD-207, IBFA, Université de Caen Basse-Normandie, Esplanade de la Paix, CS 14032, Caen Cedex 5, France; Radioecology Laboratory of Cherbourg-Octeville, Institute of Radioprotection and Nuclear Safety/PRP-ENV/SERIS, BP n 10, rue Max Pol Fouchet, Octeville, France
Recommended Citation:
Mottier A.,Séguin A.,Devos A.,et al. Effects of subchronic exposure to glyphosate in juvenile oysters (Crassostrea gigas): FROM molecular to individual levels[J]. Marine Pollution Bulletin,2015-01-01,95(2)