globalchange  > 过去全球变化的重建
DOI: 10.1016/j.marpolbul.2014.12.007
Scopus记录号: 2-s2.0-84922247728
论文题名:
Analysis of chloramphenicol residues in the macroalgae Ulva lactuca through ultra-high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS)
作者: Leston S.; Freitas A.; Nunes M.; Barbosa J.; Pardal M.T.; Ramos F.
刊名: Marine Pollution Bulletin
ISSN: 0025-326X
EISSN: 1879-3363
出版年: 2015
卷: 91, 期:1
起始页码: 180
结束页码: 184
语种: 英语
英文关键词: Chloramphenicol ; Contamination ; Macroalgae ; UHPLC-MS/MS
Scopus关键词: Animals ; Antibiotics ; Chromatography ; Contamination ; High performance liquid chromatography ; Liquids ; Mass spectrometry ; Spectrometry ; Veterinary medicine ; Broad spectrum ; Chloramphenicol ; Harmful effects ; Macro-algae ; Natural ecosystem ; Non-target organism ; U-HPLC-MS ; Ultra-high performance liquid chromatographies ; Liquid chromatography ; chloramphenicol ; antiinfective agent ; chloramphenicol ; drug residue ; water pollutant ; antibiotics ; green alga ; guideline ; liquid chromatography ; macroalga ; mass spectrometry ; aquaculture ; aquatic environment ; Article ; concentration (parameters) ; controlled study ; cost ; drug structure ; environmental monitoring ; indicator organism ; measurement precision ; measurement repeatability ; nonhuman ; process development ; process optimization ; reproducibility ; residue analysis ; solid phase extraction ; tandem mass spectrometry ; ultra performance liquid chromatography ; Ulva ; validation study ; analysis ; animal ; chemical structure ; chemistry ; high performance liquid chromatography ; procedures ; tandem mass spectrometry ; Ulva ; water pollutant ; Animalia ; Ulva lactuca ; Animals ; Anti-Bacterial Agents ; Chloramphenicol ; Chromatography, High Pressure Liquid ; Drug Residues ; Molecular Structure ; Tandem Mass Spectrometry ; Ulva ; Water Pollutants, Chemical
Scopus学科分类: Agricultural and Biological Sciences: Aquatic Science ; Earth and Planetary Sciences: Oceanography ; Environmental Science: Pollution
英文摘要: Antibiotic use is a well-described practice to promote animal health whether for prevention or treatment. Nonetheless, it can also cause a number of potentially harmful effects that dictate the need to implement regulation to assure a reduction of hazards to the consumers and the environment. Chloramphenicol (CAP) is a broad-spectrum antibacterial excluded from use in animal food production but despite this, reports of illegal use still persist. More recently, awareness has risen that the surrounding natural ecosystems can potentially be contaminated by pharmaceuticals and the extent of their effects in non-target organisms is already under the scope of researchers. To face the demanding new challenges a methodology for the determination of CAP in the green macroalgae Ulva lactuca by ultra-high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS) was developed, optimized and fully validated following the guidelines of the EC Decision 2002/657. © 2014 Elsevier Ltd.
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资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/86382
Appears in Collections:过去全球变化的重建
全球变化的国际研究计划

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作者单位: CFE - Centre for Functional Ecology, Department of Life Sciences, University of Coimbra, Apartado 3046, Coimbra, Portugal; CEF - Center for Pharmaceutical Studies, Health Sciences Campus, Pharmacy Faculty, University of Coimbra, Azinhaga de Santa Comba, Coimbra, Portugal; INIAV / LNIV - Instituto Nacional de Investigação Agrária e Veterinátia, Laboratório Nacional de Investigacão Veterinária, Estrada de Benfica 701, Lisboa, Portugal; CNC - Center for Neuroscience and Cell Biology, Pharmacy Faculty, University of Coimbra, Azinhaga de Santa Comba, Coimbra, Portugal

Recommended Citation:
Leston S.,Freitas A.,Nunes M.,et al. Analysis of chloramphenicol residues in the macroalgae Ulva lactuca through ultra-high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS)[J]. Marine Pollution Bulletin,2015-01-01,91(1)
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