DOI: 10.1016/j.marpolbul.2016.05.013
Scopus记录号: 2-s2.0-84969509994
论文题名: Variability in antioxidant/detoxification enzymes of Sinonovacula constricta exposed to benzo[a]pyrene and phenanthrene
作者: Li L. ; Jiang M. ; Shen X.
刊名: Marine Pollution Bulletin
ISSN: 0025-326X
EISSN: 1879-3363
出版年: 2016
卷: 109, 期: 1 起始页码: 507
结束页码: 511
语种: 英语
英文关键词: Antioxidant responses
; Benzo[a]pyrene(B(a)P)
; Biomarker
; Phenanthrene(PHE)
; Sinonovacula constricta
Scopus关键词: antioxidant
; benzo[a]pyrene
; glutathione transferase
; phenanthrene derivative
; superoxide dismutase
; water pollutant
; animal
; bivalve
; drug effects
; enzymology
; metabolism
; oxidative stress
; toxicity
; water pollutant
; Animals
; Antioxidants
; Benzo(a)pyrene
; Bivalvia
; Glutathione Transferase
; Oxidative Stress
; Phenanthrenes
; Superoxide Dismutase
; Water Pollutants, Chemical
Scopus学科分类: Agricultural and Biological Sciences: Aquatic Science
; Earth and Planetary Sciences: Oceanography
; Environmental Science: Pollution
英文摘要: The purpose of this study was to investigate the toxic effects induced by benzo[a]pyrene and phenanthrene. For this purpose, a study was performed on the clam exposed to 0.0, 0.5, 4.5 μgL− 1B(a)P and PHE for 15 days using parameters of antioxidant defenses and oxidative stress. Antioxidant biomarkers including ethoxyresorufin-O-deethylase, glutathione S-transferase, superoxide dismutase, and glutathione and rylhydrocarbon hydroxylasein gills of Sinonovacula constricta, were analyzed after a 1-, 3-, 9- and 15-day exposure to seawater containing B(a)P and PHE. Integrated biomarker response was calculated by combining multiple biomarkers into a single value. The results showed that the activity of all antioxidant biomarkers was induced throughout the exposure period, and different patterns of variations were detected with exposure time. In addition, the study showed that the two concentrations used caused the activation of different general detoxification mechanisms, and the same concentration at different two PAH compounds induced different toxicity responses. © 2016 Elsevier Ltd Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/86952
Appears in Collections: 过去全球变化的重建 全球变化的国际研究计划
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作者单位: East China Sea Fisheries R esearch Institute, Chinese Academy of Fishery Sciences, Shanghai, China
Recommended Citation:
Li L.,Jiang M.,Shen X.. Variability in antioxidant/detoxification enzymes of Sinonovacula constricta exposed to benzo[a]pyrene and phenanthrene[J]. Marine Pollution Bulletin,2016-01-01,109(1)