DOI: 10.1016/j.marpolbul.2015.12.022
Scopus记录号: 2-s2.0-84961223736
论文题名: Transcriptomic response to water accommodated fraction of crude oil exposure in the gill of Japanese flounder, Paralichthys olivaceus
作者: Zhu L. ; Qu K. ; Xia B. ; Sun X. ; Chen B.
刊名: Marine Pollution Bulletin
ISSN: 0025-326X
EISSN: 1879-3363
出版年: 2016
卷: 106, 期: 2018-01-02 起始页码: 283
结束页码: 291
语种: 英语
英文关键词: Gill
; Japanese flounder Paralichthys olivaceus
; Oil spill
; RNA-seq
; Transcriptome
Scopus关键词: Crude oil
; Gene expression
; Genes
; Oil spills
; RNA
; Circadian rhythms
; Expression analysis
; Gill
; Japanese flounder
; Paralichthys olivaceus
; Pathway genes
; Transcriptomes
; Water accommodated fractions
; Petroleum analysis
; biological marker
; petroleum
; transcriptome
; water pollutant
; petroleum
; adverse effects
; analysis
; animal
; drug effects
; flounder
; gene expression profiling
; genetics
; gill
; metabolism
; oil spill
; theoretical model
; toxicity
; water pollutant
; animal tissue
; Article
; circadian rhythm
; controlled study
; down regulation
; exposure
; gene control
; gene expression regulation
; gill
; high throughput sequencing
; nonhuman
; Paralichthys olivaceus
; RNA sequence
; signal transduction
; transcriptomics
; upregulation
; Animals
; Biomarkers
; Flounder
; Gene Expression Profiling
; Gills
; Models, Theoretical
; Petroleum
; Petroleum Pollution
; Transcriptome
; Water Pollutants, Chemical
; biomarker
; circadian rhythm
; crude oil
; demersal fish
; genotoxicity
; pollution effect
; pollution exposure
; RNA
; Paralichthys olivaceus
; Pisces
Scopus学科分类: Agricultural and Biological Sciences: Aquatic Science
; Earth and Planetary Sciences: Oceanography
; Environmental Science: Pollution
英文摘要: Illumina-based RNA-seq was used to determine the short-term transcriptomic responses of Paralichthys olivaceus gill to an environmentally relevant level of water accommodated fraction (WAF) of crude oil. 213,979 transcripts and 128,482 unigenes were obtained. Differential expression analysis revealed that 1641 and 2142 genes were significantly up- and down-regulated. Enrichment analysis identified a set of GO terms and putative pathways involved in the response of P. olivaceus to WAF exposure. Analysis of the transcripts revealed the effective protective mechanisms of P. olivaceus to reduce the toxic effects of WAF. Moreover, WAF exposure induced the metabolism of energy substrates, and downstream pathway genes were modified to provide protection against toxic damage. Transcripts analysis demonstrated that the genes involved in circadian rhythm signaling were regulated in gills of P. olivaceus exposed to WAF. These results provide insights into the mechanisms of WAF-induced toxicity in fishes and into the WAF-sensitive biomarkers in P. olivaceus. © 2016 Elsevier Ltd. All rights reserved. Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/87082
Appears in Collections: 过去全球变化的重建 全球变化的国际研究计划
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作者单位: Marine Fishery Environment and Bioremediation Laboratory, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Nanjing Road, Qingdao, China; Laboratory of Marine Ecology and Environmental Science, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China
Recommended Citation:
Zhu L.,Qu K.,Xia B.,et al. Transcriptomic response to water accommodated fraction of crude oil exposure in the gill of Japanese flounder, Paralichthys olivaceus[J]. Marine Pollution Bulletin,2016-01-01,106(2018-01-02)