DOI: 10.1016/j.marpolbul.2016.03.005
Scopus记录号: 2-s2.0-84960157054
论文题名: Digestive enzymatic patterns as possible biomarkers of endocrine disruption in the red mullet (Mullus barbatus): A preliminary investigation
作者: Caruso G. ; De Pasquale F. ; Mita D.G. ; Micale V.
刊名: Marine Pollution Bulletin
ISSN: 0025-326X
EISSN: 1879-3363
出版年: 2016
卷: 105, 期: 1 起始页码: 37
结束页码: 42
语种: 英语
英文关键词: Digestive enzymes
; Endocrine disruptors
; Indicators
; Northern Sicilian coast
; Red mullet
Scopus关键词: Amylases
; Biological materials
; Cost effectiveness
; Endocrine disrupters
; Enzymes
; Fish
; Fisheries
; Indicators (instruments)
; Organic pollutants
; Pollution
; Diagnostic tools
; Digestive enzymes
; Digestive tract
; Endocrine disruption
; Endocrine disruptor
; Mullus barbatus
; Red mullet
; Western Mediterranean
; Biomarkers
; amylase
; carboxypeptidase A
; carboxypeptidase B
; chymotrypsin
; pepsin A
; triacylglycerol lipase
; biological marker
; endocrine disruptor
; water pollutant
; biomarker
; endocrine disruptor
; enzyme
; organic pollutant
; perciform
; Article
; controlled study
; cost effectiveness analysis
; endocrine disease
; endocrine disruption
; energy metabolism
; environmental exposure
; environmental impact
; enzymatic pattern
; enzyme activity
; enzyme analysis
; enzyme kinetics
; enzyme localization
; enzyme release
; fish
; lipid metabolism
; Mullus barbatus
; nonhuman
; pollution monitoring
; protein content
; seasonal variation
; Southern Europe
; trend study
; animal
; digestive system
; environmental monitoring
; enzymology
; fish
; metabolism
; Perciformes
; pollution
; procedures
; sea food
; season
; Smegmamorpha
; toxicity
; water pollutant
; Italy
; Sicily
; Mullidae
; Mullus barbatus
; Animals
; Biomarkers
; Digestive System
; Endocrine Disruptors
; Environmental Monitoring
; Environmental Pollution
; Fishes
; Perciformes
; Seafood
; Seasons
; Smegmamorpha
; Water Pollutants, Chemical
Scopus学科分类: Agricultural and Biological Sciences: Aquatic Science
; Earth and Planetary Sciences: Oceanography
; Environmental Science: Pollution
英文摘要: During two seasonal trawl surveys (April and October, 2012), red mullet specimens were caught from two sites of the northern Sicilian coast (Western Mediterranean), characterized by different degrees of pollution, to assess whether their digestive enzymes could be cost-effective diagnostic tools for endocrine disruption. Pepsin, chymotrypsin, carboxypeptidases A and B, amylase and lipase were measured in the digestive tract of each fish. During both samplings, significant differences in the digestive enzymatic patterns of fish collected from the two sites were found. In April, pepsin and lipase contents were significantly lower in fish from the most impacted site than in those from the reference site. In October, the enzymatic patterns showed trends different from spring, with controversial results for carboxypeptidases A and B and amylase. Pepsin and lipase patterns suggest a detrimental effect played by organic pollutants and the use of these enzymes as possible biomarkers of exposure to endocrine disruptors. © 2016 Elsevier Ltd. Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/87130
Appears in Collections: 过去全球变化的重建 全球变化的国际研究计划
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作者单位: Institute for Coastal Marine Environment (IAMC), National Research Council (CNR), Messina, Italy; Inst. of Genetics and Biophysics Adriano Buzzati-Traverso, National Research Council (CNR), Napoli, Italy; Interuniversity Consortium of Structural and Systems Biology, Roma, Italy
Recommended Citation:
Caruso G.,De Pasquale F.,Mita D.G.,et al. Digestive enzymatic patterns as possible biomarkers of endocrine disruption in the red mullet (Mullus barbatus): A preliminary investigation[J]. Marine Pollution Bulletin,2016-01-01,105(1)