Agricultural and Biological Sciences: Aquatic Science
; Earth and Planetary Sciences: Oceanography
; Environmental Science: Pollution
英文摘要:
This study was designed to identify in the pearl oyster Pinctada margaritifera, used as a bio-accumulator, molecular biomarkers for the presence of heavy metals in the lagoon environment. Pearl oysters were exposed to 2 concentrations (1 and 10�μg�L−�1) of cadmium (Cd) and chromium (Cr) compared to a control. Twelve target genes encoding proteins potentially involved in the response to heavy metal contamination with antioxidant, detoxification or apoptosis activities were selected. P. margaritifera accumulated Cd but not Cr, and mortality was related to the amount of Cd accumulated in tissues. In response to Cd-Cr contamination, metallothionein (MT) was significantly up-regulated by Cd-Cr at both concentrations, while 7 others (SOD, CAT, GPX, GSTO, GSTM, CASP, MDR) were down-regulated. Based on the development of these molecular tools, we propose that the pearl oyster, P. margaritifera, could be used as a sentinel species for heavy metal contamination in the lagoons of tropical ecosystems. � 2017 Elsevier Ltd
Ifremer, UMR 241 EIO, UPF-ILM-IRD, Labex Corail, BP 49, Taravao, Tahiti, French Polynesia; Ifremer, UMR 5244 IHPE, UPVD, CNRS, Universit� de Montpellier, CC 80, Montpellier, France; IRSN – LESE, BP 182, Vairao, Tahiti, French Polynesia; Labex Corail, USR 3278 CNRS-CRIOBE- EPHE, Perpignan, France, Papetoai, Moorea, French Polynesia
Recommended Citation:
Gueguen Y.,Denis S.,Adrien S.,et al. Response of the pearl oyster Pinctada margaritifera to cadmium and chromium: Identification of molecular biomarkers[J]. Marine Pollution Bulletin,2017-01-01,118(2018-01-02)