globalchange  > 过去全球变化的重建
DOI: 10.1016/j.marpolbul.2016.12.055
Scopus记录号: 2-s2.0-85009804167
论文题名:
Assessment of microplastic-sorbed contaminant bioavailability through analysis of biomarker gene expression in larval zebrafish
作者: Sleight V.A.; Bakir A.; Thompson R.C.; Henry T.B.
刊名: Marine Pollution Bulletin
ISSN: 0025-326X
EISSN: 1879-3363
出版年: 2017
卷: 116, 期:2018-01-02
起始页码: 291
结束页码: 297
语种: 英语
英文关键词: 17α-ethinylestradiol ; Bioavailability ; Danio rerio ; Microplastics ; Phenanthrene ; Sorption
Scopus关键词: Anthracene ; Biochemistry ; Contamination ; Ecosystems ; Genes ; Impurities ; Sorption ; Bioavailability ; Danio rerio ; Ethinylestradiol ; Microplastics ; Phenanthrene ; Gene expression ; biological marker ; ethinylestradiol ; microplastic ; phenanthrene ; plastic ; unclassified drug ; biological marker ; phenanthrene derivative ; plastic ; water pollutant ; bioaccumulation ; bioavailability ; biomarker ; cyprinid ; gene expression ; larva ; phenanthrene ; plastic ; Article ; benthos ; bioaccumulation ; concentration (parameters) ; contaminated fish ; controlled study ; ecotoxicity ; environmental exposure ; gene expression ; genetic analysis ; larval stage ; nonhuman ; physical chemistry ; pollution transport ; prediction ; zebra fish ; animal ; bioavailability ; gene expression ; genetics ; larva ; metabolism ; water pollutant ; zebra fish ; Danio rerio ; Animals ; Biological Availability ; Biomarkers ; Ethinyl Estradiol ; Gene Expression ; Larva ; Phenanthrenes ; Plastics ; Water Pollutants, Chemical ; Zebrafish
Scopus学科分类: Agricultural and Biological Sciences: Aquatic Science ; Earth and Planetary Sciences: Oceanography ; Environmental Science: Pollution
英文摘要: Microplastics (MPs) are prevalent in marine ecosystems. Because toxicants (termed here “co-contaminants”) can sorb to MPs, there is potential for MPs to alter co-contaminant bioavailability. Our objective was to demonstrate sorption of two co-contaminants with different physicochemistries [phenanthrene (Phe), log10Kow�=�4.57; and 17α-ethinylestradiol (EE2), log10Kow�=�3.67] to MPs; and assess whether co-contaminant bioavailability was increased after MP settlement. Bioavailability was indicated by gene expression in larval zebrafish. Both Phe and EE2 sorbed to MPs, which reduced bioavailability by a maximum of 33% and 48% respectively. Sorption occurred, but was not consistent with predictions based on co-contaminant physicochemistry (Phe having higher log10Kow was expected to have higher sorption). Contaminated MPs settled to the bottom of the exposures did not lead to increased bioavailability of Phe or EE2. Phe was 48% more bioavailable than predicted by a linear sorption model, organism-based measurements therefore contribute unique insight into MP co-contaminant bioavailability. � 2016 The Authors
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资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/87802
Appears in Collections:过去全球变化的重建
全球变化的国际研究计划

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作者单位: School of Marine Science and Engineering, Marine Biology and Ecology Research Centre, University of Plymouth, Plymouth, United Kingdom; British Antarctic Survey, Natural Environment Research Council, High Cross, Madingley Road, Cambridge, United Kingdom; Institute of Life and Earth Sciences, School of Energy, Geoscience, Infrastructure and Society, Heriot-Watt University, Edinburgh, United Kingdom; Petroleum and Environmental Geochemistry Group, School of Geography Earth and Environmental Sciences, University of Plymouth, Drake Circus, Plymouth, Devon, United Kingdom; School of Earth & Environmental Sciences, University of Portsmouth, Burnaby Road, Portsmouth, United Kingdom; Center for Environmental Biotechnology, University of Tennessee, Knoxville, TN, United States; Department of Forestry, Wildlife and Fisheries, University of Tennessee, Knoxville, TN, United States

Recommended Citation:
Sleight V.A.,Bakir A.,Thompson R.C.,et al. Assessment of microplastic-sorbed contaminant bioavailability through analysis of biomarker gene expression in larval zebrafish[J]. Marine Pollution Bulletin,2017-01-01,116(2018-01-02)
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