Aromatic hydrocarbons
; Bioassay
; Chemical analysis
; Conservation
; Environmental protection
; Hydrocarbons
; Organic pollutants
; Polychlorinated biphenyls
; Rivers
; Sediments
; 2 ,3 ,7 ,8-Tetrachlorodibenzo-p-dioxin equivalents
; AhR agonists
; Aryl hydrocarbon receptor
; Cell bioassay
; Dioxin-like polychlorinated biphenyls
; Polychlorinated dibenzo-p-dioxins and dibenzofurans
; Polycyclic aromatic hydrocarbons (PAHS)
; Sediment extracts
; Polycyclic aromatic hydrocarbons
; agents interacting with transmitter, hormone or drug receptors
; aryl hydrocarbon receptor agonist
; dibenzofuran
; polychlorinated biphenyl
; polycyclic aromatic hydrocarbon
; unclassified drug
; aromatic hydrocarbon receptor
; benzofuran derivative
; polychlorinated biphenyl
; polychlorinated dibenzodioxin
; polycyclic aromatic hydrocarbon
; water pollutant
; bioassay
; concentration (composition)
; fluvial deposit
; PAH
; PCDD
; PCDF
; protected area
; sediment pollution
; Article
; China
; concentration (parameters)
; controlled study
; geographic distribution
; river
; sediment
; water analysis
; water pollutant
; water quality
; agonists
; analysis
; chemistry
; sediment
; China
; Liaohe River
; Benzofurans
; China
; Geologic Sediments
; Polychlorinated Biphenyls
; Polychlorinated Dibenzodioxins
; Polycyclic Aromatic Hydrocarbons
; Receptors, Aryl Hydrocarbon
; Rivers
; Water Pollutants, Chemical
Scopus学科分类:
Agricultural and Biological Sciences: Aquatic Science
; Earth and Planetary Sciences: Oceanography
; Environmental Science: Pollution
英文摘要:
A total of 9 sediment samples of Liaohe River protected areas were collected to evaluate aryl hydrocarbon receptor agonists (AhR-agonists) and AhR-agonist activity via chemical analysis and in vitro H4IIE cell bioassay. Results indicated that bioassay-derived 2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents (Bio-TEQs) ranged from 89.1 to 251.1�pg/g dry weight. Concentrations of 16 EPA polycyclic aromatic hydrocarbons (PAHs), 12 dioxin-like polychlorinated biphenyls (PCBs), and polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) ranged from 256.8 to 560.1�ng/g, 79.2 to 416.2�pg/g, and 199.6 to 538.4�pg/g, respectively. According to potency balance analysis, TEQchems based on PAHs, PCBs, and PCDD/Fs could contribute 16.56% to 26.11% of Bio-TEQs. This could be explained by the potential existence of unidentified AhR-agonists and the potential non-additive interactions among AhR-agonists in sediment extracts. Through the different contributions to Bio-TEQs, this study confirms that PCDD/Fs were the main pollutants that induced significantly AhR-agonist activity in sediments of Liaohe River protected areas. � 2016
Northeast Key Laboratory of Arable Land Conservation and Improvement, Ministry of Agriculture, National Engineering Laboratory for Efficient Utilization of Soil and Fertilizer Resources, College of Land and Environment, Shenyang Agricultural University, Shenyang, China; College of Energy and Environment, Shenyang Aerospace University, Shenyang, China; Department of Pharmacy, Land force General Hospital of PLA, Beijing, China
Recommended Citation:
Zhang Y.,Ke X.,Gui S.,et al. Evaluation of AhR-agonists and AhR-agonist activity in sediments of Liaohe River protected areas, China[J]. Marine Pollution Bulletin,2017-01-01,115(2018-01-02)