The liver transcriptome of suckermouth armoured catfish (Pterygoplichthys anisitsi, Loricariidae): Identification of expansions in defensome gene families
Biochemistry
; Genes
; Pollution control
; Transcription factors
; ABC transporter
; Anthropogenic chemicals
; ATP binding cassette transporters
; Nuclear receptors
; P450
; Physiological features
; Subtropical regions
; SULT
; Expansion
; ABC transporter
; cell nucleus receptor
; cytochrome P450
; cytochrome P450 2AA
; cytochrome P450 2Y
; messenger RNA
; sulfotransferase
; sulfotransferase 1A1
; transcriptome
; unclassified drug
; xenobiotic agent
; transcriptome
; fish
; physiology
; RNA
; xenobiotics
; animal tissue
; Article
; biodiversity
; catfish
; defensome gene
; gene
; gene function
; gene identification
; genetic resource
; genetic variability
; invasive species
; liver
; mitochondrial genome
; multigene family
; nonhuman
; nucleotide sequence
; protein function
; Pterygoplichthys anisitsi
; RNA sequence
; animal
; catfish
; liver
; metabolism
; multigene family
; South America
; South America
; Loricariidae
; Pterygoplichthys
; Animals
; Catfishes
; Liver
; Multigene Family
; South America
; Transcriptome
Scopus学科分类:
Agricultural and Biological Sciences: Aquatic Science
; Earth and Planetary Sciences: Oceanography
; Environmental Science: Pollution
英文摘要:
Pterygoplichthys is a genus of related suckermouth armoured catfishes native to South America, which have invaded tropical and subtropical regions worldwide. Physiological features, including an augmented resistance to organic xenobiotics, may have aided their settlement in foreign habitats. The liver transcriptome of Pterygoplichthys anisitsi was sequenced and used to characterize the diversity of mRNAs potentially involved in the responses to natural and anthropogenic chemicals. In total, 66,642 transcripts were assembled. Among the identified defensome genes, cytochromes P450 (CYP) were the most abundant, followed by sulfotransferases (SULT), nuclear receptors (NR) and ATP binding cassette transporters (ABC). A novel expansion in the CYP2Y subfamily was identified, as well as an independent expansion of the CYP2AAs. Two expansions were also observed among SULT1. Thirty-two transcripts were classified into twelve subfamilies of NR, while 21 encoded ABC transporters. The diversity of defensome transcripts sequenced herein could contribute to this species' resistance to organic xenobiotics. � 2016 Elsevier Ltd
Laborat�rio de Toxicologia Ambiental, Escola Nacional de Sa�de P�blica (ENSP), Funda��o Oswaldo Cruz (FIOCRUZ), Rio de Janeiro, Brazil; Laborat�rio de Gen�tica Molecular de Microrganismos, Instituto Oswaldo Cruz (IOC), Funda��o Oswaldo Cruz (FIOCRUZ), Rio de Janeiro, Brazil; Unidade de Gen�mica, Instituto Nacional do Cancer (INCA), Rio de Janeiro, Brazil; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, United States; Woods Hole Oceanographic Institution (WHOI), Woods Hole, MA, United States
Recommended Citation:
Parente T.E.,Moreira D.A.,Magalh�es M.G.P.,et al. The liver transcriptome of suckermouth armoured catfish (Pterygoplichthys anisitsi, Loricariidae): Identification of expansions in defensome gene families[J]. Marine Pollution Bulletin,2017-01-01,115(2018-01-02)