DOI: 10.1016/j.marpolbul.2017.12.039
Scopus记录号: 2-s2.0-85038637259
论文题名: Acute exposure to TiO2 nanoparticles produces minimal apparent effects on oyster, Crassostrea virginica (Gmelin), hemocytes
作者: Doyle J.J. ; Ward J.E. ; Wikfors G.H.
刊名: Marine Pollution Bulletin
ISSN: 0025-326X
EISSN: 1879-3363
出版年: 2018
卷: 127 起始页码: 512
结束页码: 523
语种: 英语
英文关键词: Hemocytes
; Nanoparticles
; Oyster
; Photoactivation
; ROS
; Titania
Scopus关键词: Antigen-antibody reactions
; Immunology
; Molluscs
; Nanoparticles
; Oxide minerals
; Shellfish
; Titanium compounds
; Anatase nanoparticles
; Crassostrea virginica
; Hemocytes
; Oyster
; Photo activations
; Reactive oxygen species
; TiO2 nano-particles
; Titania
; Titanium dioxide
; biological marker
; nanocomposite
; reactive oxygen metabolite
; titanium dioxide nanoparticle
; biomarker
; concentration (composition)
; mollusc
; mortality
; nanoparticle
; reactive oxygen species
; titanium
; acute toxicity
; animal cell
; Article
; blood cell
; concentration (parameters)
; controlled study
; Crassostrea virginica
; darkness
; exposure
; flow cytometry
; in vitro study
; light
; mortality
; nonhuman
; phagocytosis
; Crassostrea virginica
; Ostreidae
Scopus学科分类: Agricultural and Biological Sciences: Aquatic Science
; Earth and Planetary Sciences: Oceanography
; Environmental Science: Pollution
英文摘要: The response of oyster (Crassostrea virginica) hemocytes was studied following exposure to anatase nanoparticles (ca. 7.4 nm), surface-coated rutile nanocomposites (UV–Titan M212, ca. 86 nm) and bulk titanium dioxide (TiO2) particles (anatase and rutile crystalline forms; ca. 2–5 μm). Hemocytes were collected from oysters and exposed to one of the four particle types at concentrations of 0.1, 0.5, and 1.0 mg/L under dark and environmentally-relevant light conditions for periods of two and four hours. Hemocyte mortality, phagocytosis, and reactive oxygen species (ROS) production were then evaluated using flow-cytometric assays. Bulk and nanoparticulate TiO2 had little effect on viability of oyster hemocytes or on production of ROS. Significant changes in phagocytosis occurred after exposure to anatase nanoparticles for 4 h under dark conditions, and UV–Titan for 2 h under light conditions. Results demonstrate that TiO2 particles (bulk or nanoscale) produce minimal effects on hemocyte biomarkers examined following acute, in vitro exposures. © 2017 Elsevier Ltd Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/88478
Appears in Collections: 过去全球变化的重建 全球变化的国际研究计划
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作者单位: Gloucester Marine Genomics Institute, 55 Blackburn Center, Gloucester, MA, United States; University of Connecticut, Department of Marine Sciences, 1080 Shennecossett Road, Groton, CT, United States; National Oceanic and Atmospheric Administration, Northeast Fisheries Science Center, 212 Rogers Avenue, Milford, CT, United States
Recommended Citation:
Doyle J.J.,Ward J.E.,Wikfors G.H.. Acute exposure to TiO2 nanoparticles produces minimal apparent effects on oyster, Crassostrea virginica (Gmelin), hemocytes[J]. Marine Pollution Bulletin,2018-01-01,127