globalchange  > 过去全球变化的重建
DOI: 10.1016/j.marpolbul.2017.11.055
Scopus记录号: 2-s2.0-85040797780
论文题名:
Characterization of endocrine disruption potentials of coastal sediments of Taean, Korea employing H295R and MVLN assays–Reconnaissance at 5 years after Hebei Spirit oil spill
作者: Liu X.; Jung D.; Zhou K.; Lee S.; Noh K.; Khim J.S.; Giesy J.P.; Yim U.H.; Shim W.J.; Choi K.
刊名: Marine Pollution Bulletin
ISSN: 0025-326X
EISSN: 1879-3363
出版年: 2018
卷: 127
起始页码: 264
结束页码: 272
语种: 英语
英文关键词: Endocrine disrupting potential ; H295R ; Hebei Spirit oil spill ; MVLN
Scopus关键词: Aromatic hydrocarbons ; Bioassay ; Crude oil ; Oil spills ; Sediments ; Silica ; Coastal sediments ; Endocrine disrupting potential ; Endocrine disruption ; Estrogen receptor binding ; H295R ; MVLN ; Polar compounds ; Sediment samples ; Endocrine disrupters ; aromatic hydrocarbon ; estradiol ; estrogen receptor ; petroleum ; polycyclic aromatic hydrocarbon ; silicon dioxide ; bioassay ; chemical weathering ; coastal sediment ; crude oil ; endocrine disruptor ; fractionation ; oil spill ; PAH ; sediment pollution ; Article ; binding affinity ; cell assay ; coastal sediment ; concentration (parameters) ; controlled study ; cytotoxicity ; ecotoxicology ; endocrine disruption potential ; environmental parameters ; fractionation ; human ; human cell ; MVLN cell line ; NCI-H295R cell line ; oil spill ; receptor binding ; sediment ; South Korea ; steroidogenesis ; trend study ; water analysis ; weathering ; South Chungcheong ; South Korea ; Taean
Scopus学科分类: Agricultural and Biological Sciences: Aquatic Science ; Earth and Planetary Sciences: Oceanography ; Environmental Science: Pollution
英文摘要: Endocrine disrupting potentials were assessed for sediment samples collected near Hebei Spirit oil spill (HSOS) site, between December 2007 and January 2012. For comparison, major crude oil (CO) of HSOS, or its weathered form were assessed. Both raw extracts (REs) and their fractionated samples were tested using H295R and MVLNluc bioassays. In H295R cells, REs of crude and weathered oil (WO), and nine of 14 sediments significantly increased E2 levels, which were correlated with the concentrations of PAHs. Steroidogenic disruption potentials of the sediments generally decreased over time. Among silica fractions of all REs, aromatic hydrocarbons (F2) and polar compounds (F3) caused greater E2 levels. While, in MVLN cell bioassay, only three of 14 sediment REs showed estrogen receptor binding potencies, and no temporal trend was observed. In conclusion, oil spill can cause endocrine disruption in the affected ecosystem through steroidogenic alteration for years, and such potencies attenuate over time. © 2017 Elsevier Ltd
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资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/88489
Appears in Collections:过去全球变化的重建
全球变化的国际研究计划

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作者单位: Dongguan Key Laboratory of Environmental Medicine, School of Public Health, Guangdong Medical UniversityGuangdong, China; School of Public Health & Institute of Health and Environment, Seoul National University, Seoul, South Korea; Korea Environment Institute, Sejong, South Korea; Korea Institute of Toxicology, Daejeon, South Korea; School of Earth and Environmental Sciences & Research Institute of Oceanography, Seoul National University, Seoul, South Korea; Department of Veterinary Biomedical Sciences & Toxicology Centre, University of Saskatchewan, Saskatoon, SK, Canada; Oil and POPs Research Group, Korea Institute of Ocean Science and Technology (KIOST), Geoje, South Korea

Recommended Citation:
Liu X.,Jung D.,Zhou K.,et al. Characterization of endocrine disruption potentials of coastal sediments of Taean, Korea employing H295R and MVLN assays–Reconnaissance at 5 years after Hebei Spirit oil spill[J]. Marine Pollution Bulletin,2018-01-01,127
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