| 项目编号: | 1554095
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| 项目名称: | CAREER: The mechanics and control of cell dispersal |
| 作者: | Jeffrey Guasto
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| 承担单位: | Tufts University
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| 批准年: | 2016
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| 开始日期: | 2016-09-01
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| 结束日期: | 2021-08-31
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| 资助金额: | 518676
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| 资助来源: | US-NSF
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| 项目类别: | Standard Grant
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| 国家: | US
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| 语种: | 英语
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| 特色学科分类: | Engineering - Chemical, Bioengineering, Environmental, and Transport Systems
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| 英文关键词: | cell
; swimming
; career proposal
; individual cell
; real bacterium cell
; cell transport
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| 英文摘要: | PI: Guasto, Jeffrey
Proposal Number: 1554095
This CAREER proposal is focused on the investigation of how the material properties of viscous fluids affect the motion of cells. The goal is to contribute insights into the broad field of cell transport, and to understand how different physical processes affecting the swimming of cells can regulate a host of diverse biological functions. The results of this research could have an impact on multiple fields, including public health, ecology, engineering and medicine. Phenomena that are important to the treatment of fertility and the mechanisms of spreading of disease will be investigated.
While most prior work in this area has been focused on cases of swimming in Newtonian fluids (aquatic environments mainly), and ideally shaped swimmers, this is a proposal to investigate the swimming of real bacteria cells and in non-Newtonian fluids, like cervical mucus. The development of a novel nano-scale experimental technique, based on high speed imaging, for the monitoring of the motion of each individual cell is also proposed. In addition to graduate and undergraduate student training, a new outreach program (STOMP) will be developed in collaboration with Tufts Center for Engineering Education and Outreach that will be based on using high-speed imaging. |
| 资源类型: | 项目
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| 标识符: | http://119.78.100.158/handle/2HF3EXSE/91030
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| Appears in Collections: | 全球变化的国际研究计划
科学计划与规划
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| Recommended Citation: | |
Jeffrey Guasto. CAREER: The mechanics and control of cell dispersal. 2016-01-01.
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