| 项目编号: | 1637863
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| 项目名称: | EAGER: A Novel Method for Simultaneous Enrichment and Detection of Bacterial Cells |
| 作者: | Ramaraja Ramasamy
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| 承担单位: | University of Georgia Research Foundation Inc
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| 批准年: | 2016
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| 开始日期: | 2016-08-01
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| 结束日期: | 2018-07-31
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| 资助金额: | 150314
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| 资助来源: | US-NSF
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| 项目类别: | Standard Grant
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| 国家: | US
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| 语种: | 英语
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| 特色学科分类: | Engineering - Chemical, Bioengineering, Environmental, and Transport Systems
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| 英文关键词: | early detection
; novel method
; rapid detection
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| 英文摘要: | PI Ramasamy, Ramaraja P.
Proposal No 1637863
Rapid and early detection of pathogens during food processing operations is strategic for preventing contamination, improving food safety, quality and hygiene. The proposed project would provide a near-ideal solution for this identified problem.
Rapid and early detection of pathogens in food processing operations is strategic for preventing contamination, improving food safety, quality and hygiene. The proposed project will develop a near-ideal solution to this problem. A novel method for simultaneous isolation (enrichment) and detection of a foodborne pathogen, Listeria monocytogenes, from complex food matrices using bacteriophage as bio-recognition entity will be characterized. Because available antibodies for Listeria monocytogenes have poor avidity, the PI will genetically engineer bacteriophage for this specific purpose. Specific research objectives are: (1) isolate L. monocytogenes by magnetic separation from model food matrix using recombinant A511 phage. (2) Demonstrate rapid detection of L. monocytogenes on A511 modified electrodes using AC impedance. Education and outreach objectives are to broaden participation of women in engineering, promote diversity in STEM disciplines and provide interdisciplinary education for engineering undergraduate students.
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| 资源类型: | 项目
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| 标识符: | http://119.78.100.158/handle/2HF3EXSE/91625
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| Appears in Collections: | 全球变化的国际研究计划
科学计划与规划
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| Recommended Citation: | |
Ramaraja Ramasamy. EAGER: A Novel Method for Simultaneous Enrichment and Detection of Bacterial Cells. 2016-01-01.
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