| 项目编号: | 1606136
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| 项目名称: | Positive Contrast MRI for Imaging Small Interventional Devices |
| 作者: | Jim Ji
|
| 承担单位: | Texas A&M Engineering Experiment Station
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| 批准年: | 2016
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| 开始日期: | 2016-06-15
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| 结束日期: | 2019-05-31
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| 资助金额: | 252109
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| 资助来源: | US-NSF
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| 项目类别: | Standard Grant
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| 国家: | US
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| 语种: | 英语
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| 特色学科分类: | Engineering - Chemical, Bioengineering, Environmental, and Transport Systems
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| 英文关键词: | mri
; parallel imaging
; magnetic resonance imaging
; positive-contrast imaging
; project
; biomedical imaging research
; rapid contrast mri
; imaging system
; interventional device
; interventional mri
; biomedical imaging
; small interventional device
|
| 英文摘要: | 1606136
The proficiency of Magnetic Resonance Imaging (MRI) in defining target areas for treatment makes it a powerful tool for pre-operation planning in surgical interventions. However MRI faces unique challenges when interventional devices are involved. Most devices are invisible or difficult to visualize with MRI. This project will develop a novel susceptibility mapping technology to achieve rapid contrast MRI of brachytherapy seeds for prostate cancer treatment. Longer term this technology will enable deep brain stimulation (DBS) in neurosurgery. These outcomes will be integrated in outreach and educational activities to stimulate interest in biomedical imaging among a diverse group of students. The project will promote biomedical imaging research among local high-school students and female students through an annual workshop and laboratory studies.
A key insight is that it is possible to turn the magnetic susceptibility of the small interventional devices from being a nuisance into useful information. The PI uses the magnetic susceptibility inherent in each device for positive-contrast imaging which is a novel concept in interventional MRI. This project will a) develop a fast 3D pulse sequence for susceptibility mapping that is robust in regards to image distortion; b) integrate the fast sequence, compressive sensing and parallel imaging with a wearable pelvic diaper coil to accelerate data acquisition; and c) validate this technique on a 4.7 Tesla animal scanner and on a 3 Tesla whole-body scanner using a realistic tissue-mimicking pelvic phantom. The project will be built on the preliminary work of a team of multidisciplinary investigators with complementary expertise in MR physics, imaging systems, and medical research. |
| 资源类型: | 项目
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| 标识符: | http://119.78.100.158/handle/2HF3EXSE/92079
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| Appears in Collections: | 全球变化的国际研究计划
科学计划与规划
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| Recommended Citation: | |
Jim Ji. Positive Contrast MRI for Imaging Small Interventional Devices. 2016-01-01.
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