| 项目编号: | 1605624
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| 项目名称: | Collaborative Research: SusChEM: Root-Targeted Delivery of Encapsulated Agrochemicals using Natural Microbial Carriers |
| 作者: | Leslie Shor
|
| 承担单位: | University of Connecticut
|
| 批准年: | 2016
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| 开始日期: | 2016-06-01
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| 结束日期: | 2019-05-31
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| 资助金额: | 248944
|
| 资助来源: | US-NSF
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| 项目类别: | Standard Grant
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| 国家: | US
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| 语种: | 英语
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| 特色学科分类: | Engineering - Chemical, Bioengineering, Environmental, and Transport Systems
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| 英文关键词: | root tip
; nanoencapsulated agrochemical
; collaborative project
; soil
; plant root
; fluorescent agrochemical analog
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| 英文摘要: | CBET - 1605624; 1605816
PI: Shor, Leslie; Prud'homme, Robert
The goal of this collaborative project is to develop a method to deliver chemical compounds such as herbicides, fungicides, and nematicides directly to the root tips of plants where they can be most benefit to the growth and preservation of the plant. To accomplish targeted delivery, the compounds of interest will be encapsulated in nanoparticles. Protists, which are single-cell microbes that are abundant in soil, can spontaneously engulf nanoparticles and carry them through soil. Protists are chemically attracted toward the root tips of growing plants, which means that the encapsulated compounds can be preferentially delivered to the root tips rather than being dispersed throughout all of the soil. The project will develop nanoencapsulation technology that is compatible with protist uptake and transport. The benefits of the research will be increased efficiency, reduced costs and reduced impact of chemical use in agriculture, all of which can increase crop production and promote sustainability of the farming enterprise. Students at various academic levels will participate in the project, and the project will be used as a platform for outreach activities for Connecticut high school teachers participating in the Early College Experience program.
Flash nanoprecipitation and inverse flash nanoprecipitation will be used for efficient, economic and scalable production of biocompatible particles. Fluorescent agrochemical analogs will be developed to assess encapsulation, uptake, and transport. Analogs will be developed across a wide range of hydrophobicity, which will help identify rules for feasibility and commercialization potential. Cyst-forming, non-pathogenic soil protists will be collected from agricultural soils and screened for efficient uptake of nanoencapsulated agrochemicals and transport through soil-like media. A microfluidic transport assay will be developed that emulates the physical microstructure of soil and the chemical gradients found in the immediate environment of plant roots. The microfluidic assay will enable rapid screening and collection of fundamental uptake and transport parameters needed for predictive modelling. Finally, an agent-based pore-scale transport model will be developed to characterize potential benefits of implementing this technology at the field scale. |
| 资源类型: | 项目
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| 标识符: | http://119.78.100.158/handle/2HF3EXSE/92168
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| Appears in Collections: | 全球变化的国际研究计划
科学计划与规划
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| Recommended Citation: | |
Leslie Shor. Collaborative Research: SusChEM: Root-Targeted Delivery of Encapsulated Agrochemicals using Natural Microbial Carriers. 2016-01-01.
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