| 项目编号: | 1541612
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| 项目名称: | NSF/FDA SIR: Multimodal characterization of quantitative biomarkers for traumatic brain injury measured via portable device technology |
| 作者: | Jonathan Fisher
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| 承担单位: | New York Medical College
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| 批准年: | 2014
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| 开始日期: | 2015-11-01
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| 结束日期: | 2016-10-31
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| 资助金额: | USD79768
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| 资助来源: | US-NSF
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| 项目类别: | Standard Grant
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| 国家: | US
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| 语种: | 英语
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| 特色学科分类: | Engineering - Chemical, Bioengineering, Environmental, and Transport Systems
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| 英文关键词: | tbi
; quantifiable biomarker
; tbi biomarker
; portable device
; traumatic brain injury
; pre-injury measurement
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| 英文摘要: | PI: Fisher, Jonathan
Proposal Number:1541612
This proposal, whose driving goal is the need for a portable device capable of quantifying biomarkers of traumatic brain injury (TBI), focuses on determining the utility of Electroencephalography (EEG) and Diffuse Correlation Spectrography (DCS) for detecting TBI biomarkers in an animal model.
TBI is a very significant issue in both military and civilian medicine. Diagnosis and assessment of TBI patients is generally performed using clinical imaging modalities (MRI, CT). However, the future availability of portable devices for assessing TBI would fundamentally improve the outlook for TBI patients. The diagnosis and treatment of TBI is impeded by gaps in regulatory science due to a lack of quantifiable biomarkers. Two complementary measurement parameters have potential to fill this gap. (1) measurement of somatosensory evoked electrophysiological potentials (SSEPs); and (2) diffuse correlation spectroscopy (DCS). This proposal seeks to evaluate the utility of these parameters for detecting TBI in an animal model without the need for a baseline, pre-injury measurement. |
| 资源类型: | 项目
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| 标识符: | http://119.78.100.158/handle/2HF3EXSE/93094
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| Appears in Collections: | 影响、适应和脆弱性
气候减缓与适应
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| Recommended Citation: | |
Jonathan Fisher. NSF/FDA SIR: Multimodal characterization of quantitative biomarkers for traumatic brain injury measured via portable device technology. 2014-01-01.
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