globalchange  > 影响、适应和脆弱性
项目编号: 1454334
项目名称:
CAREER: Biofluid Dynamics of the Human Breast: Characterization and Fluid-Structure Interaction
作者: Fatemeh Hassanipour
承担单位: University of Texas at Dallas
批准年: 2014
开始日期: 2015-09-01
结束日期: 2020-08-31
资助金额: USD503171
资助来源: US-NSF
项目类别: Standard Grant
国家: US
语种: 英语
特色学科分类: Engineering - Chemical, Bioengineering, Environmental, and Transport Systems
英文关键词: human breast ; fluid dynamics point ; breast-infant interaction ; fluid-structure interaction ; career proposal ; flexible structure ; pore structure ; female breast ; flow
英文摘要: 1454334
Hassanipour

The goal of this CAREER proposal is to study lactation in the human breast from a fluid dynamics point of view, considering the flow of milk as flow through a porous medium with flexible structure. Despite the scientific importance and impact on public health, bio-transport processes in the human breast have not been comprehensively studied, and are currently not well-understood. This is the white space that the current proposal aims to cover, with potential impact on the lives of millions of people. Success of the project can enable biomedical devise design and diagnosis of health conditions related to the female breast. This project has the potential for high rewards, since it can open up a completely new area of research. The societal and economic impact of understanding fundamentally the fluid-structure interaction in the human breast can be very significant, ranging from effective drug delivery to health condition diagnosis and the design of medical devises resolving lactation difficulties.

The PI is proposing to use state-of-the-art experiments and simulations to understand the bio-transport behavior of the ductal system of the human breast. Advanced imaging and 3D printing techniques are going to be used to obtain realistic images of the pore structure within human breasts and then to manufacture prototypes for laboratory and computational investigation of the flow. The breast-infant interaction and the boundary effects of infant suckling will also be investigated. The proposed research activities are further integrated with an educational component including course development, and K-12 outreach activities that are a continuation of PI's past work with high-school students.
资源类型: 项目
标识符: http://119.78.100.158/handle/2HF3EXSE/93309
Appears in Collections:影响、适应和脆弱性
气候减缓与适应

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Recommended Citation:
Fatemeh Hassanipour. CAREER: Biofluid Dynamics of the Human Breast: Characterization and Fluid-Structure Interaction. 2014-01-01.
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