项目编号: | 1501479
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项目名称: | DISSERTATION RESEARCH: Intra-annual Dynamics in the Gut Microbiota of Migratory Shorebirds |
作者: | Brett Sandercock
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承担单位: | Kansas State University
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批准年: | 2014
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开始日期: | 2015-06-01
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结束日期: | 2016-05-31
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资助金额: | USD18030
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资助来源: | US-NSF
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项目类别: | Standard Grant
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国家: | US
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语种: | 英语
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特色学科分类: | Biological Sciences - Environmental Biology
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英文关键词: | gut microbiota
; migratory shorebird
; research
; mammalian microbiota
; shorebird gut microbial composition
; gut microbial composition
; migratory population
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英文摘要: | Gut microbiota plays a vital role in organism health through facilitating nutrient uptake, detoxification and interactions with the immune system. Whereas the mammalian microbiota is predominantly shaped by underlying genetics, factors affecting the avian gut microbiota remain largely unknown. Migratory shorebirds are sensitive to environmental change as a result of their use of geographically wide-spread habitats throughout their annual cycle. The local environment thus has the potential to alter avian gut microbiota. This research will investigate environmental factors influencing gut microbiota of migratory shorebirds as their long-distance movement and intercontinental migration annually expose them to a wide range of microorganisms and potential pathogens. The overarching objective of this study is to evaluate the importance of the local environment in determining gut microbiota composition in migratory shorebirds, by assessing presence and causes of intra-annual variation in gut microbiota in relation to breeding, staging and wintering environments. Migratory shorebirds have the potential to act as disease vectors that spread pathogens over long distances, and investigation of gut microbiota diversity and function is an essential first step towards identifying current and future disease threats to both avian and human populations.
The overall objective of this research will be addressed by testing three hypotheses related to different aspects of environment-gut microbiota interactions: site characteristics, duration of stay, and interactions among migratory populations. The researchers predict that the local environment largely determines gut microbial composition, and that within this environment the effect of latitude and flock composition on gut microbiota composition will be detectable. Shorebird gut microbial composition will be analyzed from fecal samples collected from key shorebird staging and wintering sites throughout the Western Hemisphere. Bacterial communities will be sequenced using genetic techniques and microbial communities will be analyzed by using advanced bioinformatics and a Bayesian statistical framework. This research combines the fields of migration ecology, microbiology and computational biology. |
资源类型: | 项目
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标识符: | http://119.78.100.158/handle/2HF3EXSE/94504
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Appears in Collections: | 影响、适应和脆弱性 气候减缓与适应
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Recommended Citation: |
Brett Sandercock. DISSERTATION RESEARCH: Intra-annual Dynamics in the Gut Microbiota of Migratory Shorebirds. 2014-01-01.
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