| 项目编号: | 1512043
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| 项目名称: | UNS:Multiresonator Photonic Crystal Enhanced Fluorescence and SERS |
| 作者: | Brian Cunningham
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| 承担单位: | University of Illinois at Urbana-Champaign
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| 批准年: | 2014
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| 开始日期: | 2015-05-15
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| 结束日期: | 2018-04-30
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| 资助金额: | USD600526
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| 资助来源: | US-NSF
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| 项目类别: | Standard Grant
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| 国家: | US
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| 语种: | 英语
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| 特色学科分类: | Engineering - Chemical, Bioengineering, Environmental, and Transport Systems
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| 英文关键词: | sers assay
; photonic crystal resonator surface
; fluorescence detection
; surface-based fluorescence assay
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| 英文摘要: | Abstract
Cunningham, Brian
1512043
The goal of this proposal is to develop a novel approach for coupling multiple optical cavities together to enhance the excitation of fluorescent emitters used for biological and chemical detection. Wavelength-tuned external cavity lasers, photonic crystal resonator surfaces, and gold nanorods are combined to demonstrate large enhanced fluorescence detection of proteins.
Surface-based fluorescence assays and surface enhanced Raman scattering (SERS) are widely used in life science research, molecular diagnostics, and microscopy. There is strong motivation to improve their detection sensitivity while at the same time reducing the cost/complexity of detection instrumentation. This project would develop and characterize a fundamentally new approach towards excitation of surface-adsorbed photon emitters and scatterers that can be applied towards surface-based fluorescent and SERS assays for biomolecular analytes used in life science research, genomics, proteomics, diagnostics, and environmental monitoring. The approach incorporates inexpensively manufacturable nanostructured surfaces and an nexpensive, compact detection instrument that will facilitate broad adoption. The project involves graduate research, undergraduate internships, integration of laboratory demonstrations into undergraduate courses, and activities that involve hands-on demonstrations to middle school children. |
| 资源类型: | 项目
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| 标识符: | http://119.78.100.158/handle/2HF3EXSE/94665
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| Appears in Collections: | 影响、适应和脆弱性
气候减缓与适应
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| Recommended Citation: | |
Brian Cunningham. UNS:Multiresonator Photonic Crystal Enhanced Fluorescence and SERS. 2014-01-01.
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