| 项目编号: | 1457523
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| 项目名称: | Cityscape Genomics of Rats in New York City |
| 作者: | Jason Munshi-South
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| 承担单位: | Fordham University
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| 批准年: | 2014
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| 开始日期: | 2015-05-01
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| 结束日期: | 2018-04-30
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| 资助金额: | USD672071
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| 资助来源: | US-NSF
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| 项目类别: | Standard Grant
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| 国家: | US
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| 语种: | 英语
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| 特色学科分类: | Biological Sciences - Environmental Biology
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| 英文关键词: | city
; rat
; new york city
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| 英文摘要: | Brown rats (also known as Norway or sewer rats) are one of the most common mammals in the world, and cause significant damage to human health and infrastructure. Cities in particular harbor very large rat populations, but their biology is poorly known. This study will address novel and important questions about the evolutionary and ecological processes occurring in the built environment using the infamous rat population in New York City. What specific types of urban infrastructure, such as sewers or subways, do rats use to move through the city? Are rat movements associated with socioeconomics of human neighborhoods? Where did NYC rats come from, and how are they related to other populations around the world? How have rats evolved since they invaded NYC in the 18th century? Results from this project will also be used to introduce students and the public to evolutionary biology by funding art projects and innovative curricular materials.
Several complementary genomic approaches will be used to understand the evolution of brown rats from local to global scales. First, landscape modeling based on structural and socioeconomic characteristics of NYC will shed light on the drivers of local population structure and movements of rats within NYC. Next, signatures of historical population size changes and ancestry that are encoded in the genomes of rats from around the world will then be examined. Within NYC, genes involved in recent adaptation to the urban environment will also be identified. Finally, these evolutionary changes will be confirmed using DNA extracted from museum specimens of rats collected over the last 125 years. |
| 资源类型: | 项目
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| 标识符: | http://119.78.100.158/handle/2HF3EXSE/94699
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| Appears in Collections: | 影响、适应和脆弱性
气候减缓与适应
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| Recommended Citation: | |
Jason Munshi-South. Cityscape Genomics of Rats in New York City. 2014-01-01.
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