项目编号: | 1514673
|
项目名称: | RAPID: Optimal allocation of both non-pharmaceutical and pharmaceutical interventions toward controlling Ebola virus transmission in West Africa |
作者: | Alison Galvani
|
承担单位: | Yale University
|
批准年: | 2013
|
开始日期: | 2014-12-15
|
结束日期: | 2016-02-29
|
资助金额: | USD199890
|
资助来源: | US-NSF
|
项目类别: | Standard Grant
|
国家: | US
|
语种: | 英语
|
特色学科分类: | Biological Sciences - Environmental Biology
|
英文关键词: | non-pharmaceutical public health intervention
; model
; west africa ebola outbreak
; resource allocation
; west africa
|
英文摘要: | This research will evaluate the success of various pharmaceutical and public health strategies in the 2014 West Africa Ebola outbreak in order to most effectively control and reduce the spread of disease. The investigators will develop a mathematical model that considers variability in a person?s infectiousness, the variation in transmission that occurs in a hospital or community setting, as well as the differences in transmission due to geography and spatial variation. This proposed tool will utilize current data from the outbreak in West Africa to accurately reflect the on-the-ground situation. Consequently, results from this research will provide immediately relevant and real-time information.
The investigators are utilizing contact tracing data collected by the Liberian Ministry of Health and Social Welfare. This dataset of 1360 cases and 7400 traced contacts from the current outbreak will be used to parameterize the model. The data will provide information on individual behavior changes in response to disease spread, between-community movement and self-quarantining measures. Pharmaceutical data including experimental vaccines, as well as community based antiviral therapies such as ZMapp and favipiravir will be evaluated in the model. The following non-pharmaceutical public health interventions will be evaluated in the model: quantity of public health personnel and ambulance services, magnitude of treatment center capacity, and the allocation and efficacy of household protective kits. This tool will offer important information to public health professionals to assist them in making critical decisions on resource allocation in order to maximize impact and public health outcomes. |
资源类型: | 项目
|
标识符: | http://119.78.100.158/handle/2HF3EXSE/95328
|
Appears in Collections: | 影响、适应和脆弱性 气候减缓与适应
|
There are no files associated with this item.
|
Recommended Citation: |
Alison Galvani. RAPID: Optimal allocation of both non-pharmaceutical and pharmaceutical interventions toward controlling Ebola virus transmission in West Africa. 2013-01-01.
|
|
|