| 项目编号: | 1445342
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| 项目名称: | EAGER: Portable photoacoustic platform for glucose sensing |
| 作者: | Sergey Mirov
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| 承担单位: | University of Alabama at Birmingham
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| 批准年: | 2013
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| 开始日期: | 2014-10-01
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| 结束日期: | 2017-09-30
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| 资助金额: | USD299942
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| 资助来源: | US-NSF
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| 项目类别: | Standard Grant
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| 国家: | US
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| 语种: | 英语
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| 特色学科分类: | Engineering - Chemical, Bioengineering, Environmental, and Transport Systems
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| 英文关键词: | device
; portable photoacoustic platform
; glucose level monitoring
; eager
; glucose sensingthe pi
; blood glucose level monitoring
; weak glucose absorption signal
; continuous blood glucose level monitoring
; blood glucose level
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| 英文摘要: | Proposal: 1445342
PI: Mirov, Sergey
University: University of Alabama at Birmingham
Title: EAGER: Portable photoacoustic platform for glucose sensing
The PI proposes to develop and build a working prototype of a true noninvasive, portable hand held, low cost device for blood glucose level monitoring in home or clinic settings. If successful, this device will substantially improve the quality of life of millions of people with diabetes by eliminating discomfort and pain associated with the necessity to puncture fingers, and reduce the probability of developing chronic diabetes complications due to poor management of blood glucose levels. The device could be also used for continuous blood glucose level monitoring in clinic and hospital settings. The proposed platform can also be used for development of other applications such as detection and monitoring of chemicals of interest in aqueous solutions for environmental studies, and in industrial settings.
The device will be based on a wavelength modulation (WM) photoacoustic (PA) spectroscopy in the near-infra-red (IR) spectral region. It will consist of a portable acoustic cell, a portable broadly tunable diode pumped Cr:ZnSe laser, pioneered by the PI group, and a smartphone for measurements control and data analysis. This novel wavelength modulation technique is essentially a zero background method, which will substantially improve sensitivity of current photoacoustic methods for glucose level monitoring. The absence of a strong background due to water absorption will not only improve sensitivity of the device, but also eliminate the necessity to perform arduous data treatment algorithms for extracting weak glucose absorption signals masked under a strong background. This will enable the use of devices with low computational power, such as smartphones. |
| 资源类型: | 项目
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| 标识符: | http://119.78.100.158/handle/2HF3EXSE/95445
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| Appears in Collections: | 影响、适应和脆弱性
气候减缓与适应
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| Recommended Citation: | |
Sergey Mirov. EAGER: Portable photoacoustic platform for glucose sensing. 2013-01-01.
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