| 项目编号: | 1406876
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| 项目名称: | DISSERTATION RESEARCH: Phylogeographic analysis of introgressive gene flow among nuclear loci functionally linked to the mitochondrion |
| 作者: | David Weisrock
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| 承担单位: | University of Kentucky Research Foundation
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| 批准年: | 2013
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| 开始日期: | 2014-07-01
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| 结束日期: | 2017-06-30
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| 资助金额: | USD19485
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| 资助来源: | US-NSF
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| 项目类别: | Standard Grant
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| 国家: | US
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| 语种: | 英语
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| 特色学科分类: | Biological Sciences - Environmental Biology
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| 英文关键词: | gene flow
; genetic divergence
; nuclear gene
; genetic technology
; peer-reviewed research
; nuclear-encoded mitochondrial gene
; genetic study
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| 英文摘要: | Genetic studies across species frequently uncover conflicting patterns between the nuclear and organellar (including mitochondria) genomes. Contrasting patterns of genomic divergence can potentially be explained by differences related to inheritance, gene flow, and mutation rate, but it is unknown how co-evolutionary interactions between these genomes influence genetic divergence. Using Dusky Salamanders and revolutionary DNA sequencing technologies, evolutionary patterns of divergence will be compared between the nuclear and mitochondrial genomes, with a focus on nuclear genes that function within the mitochondrion. Dusky salamanders are an excellent system for this project because they are regionally diverse in eastern North America and have demonstrated gene flow across species boundaries. These criteria, and the growing genetic resources available for salamanders, make them an excellent system to test for conflicting evolutionary patterns between nuclear and nuclear-encoded mitochondrial genes.
This research will contribute toward graduate student training in the use of rapidly changing and advancing genetic technologies and help preparations for an academic career through peer-reviewed research and undergraduate mentorship. Results from this study will provide new insights into how researchers should use genomic data to reconstruct the Tree of Life, and will contribute to an understanding of the processes that influence genetic divergence and speciation. |
| 资源类型: | 项目
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| 标识符: | http://119.78.100.158/handle/2HF3EXSE/96494
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| Appears in Collections: | 影响、适应和脆弱性
气候减缓与适应
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| Recommended Citation: | |
David Weisrock. DISSERTATION RESEARCH: Phylogeographic analysis of introgressive gene flow among nuclear loci functionally linked to the mitochondrion. 2013-01-01.
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